IRIS
SECONDO, Agnese
 Distribuzione geografica
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Continente #
NA - Nord America 3.702
AS - Asia 2.540
EU - Europa 1.553
SA - Sud America 587
AF - Africa 101
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.488
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Nazione #
US - Stati Uniti d'America 3.613
SG - Singapore 810
RU - Federazione Russa 622
VN - Vietnam 554
BR - Brasile 451
HK - Hong Kong 429
CN - Cina 396
IT - Italia 214
FR - Francia 161
SE - Svezia 90
UA - Ucraina 90
DE - Germania 67
GB - Regno Unito 67
IE - Irlanda 61
AR - Argentina 52
MX - Messico 50
BD - Bangladesh 49
IN - India 48
TR - Turchia 41
FI - Finlandia 37
IQ - Iraq 35
NL - Olanda 30
DK - Danimarca 29
EC - Ecuador 26
ZA - Sudafrica 25
PL - Polonia 24
CI - Costa d'Avorio 23
CA - Canada 22
ID - Indonesia 21
AT - Austria 20
KR - Corea 19
CO - Colombia 16
UZ - Uzbekistan 16
MA - Marocco 15
SA - Arabia Saudita 15
VE - Venezuela 14
JP - Giappone 13
PH - Filippine 13
PK - Pakistan 13
ES - Italia 11
AE - Emirati Arabi Uniti 10
KE - Kenya 10
MY - Malesia 9
JO - Giordania 8
NP - Nepal 8
LT - Lituania 7
UY - Uruguay 7
CL - Cile 6
PY - Paraguay 6
AZ - Azerbaigian 5
BO - Bolivia 5
EG - Egitto 5
TN - Tunisia 5
BE - Belgio 4
DZ - Algeria 4
KZ - Kazakistan 4
PA - Panama 4
AL - Albania 3
ET - Etiopia 3
JM - Giamaica 3
PE - Perù 3
BG - Bulgaria 2
BH - Bahrain 2
CR - Costa Rica 2
DO - Repubblica Dominicana 2
GR - Grecia 2
HN - Honduras 2
HU - Ungheria 2
IL - Israele 2
KW - Kuwait 2
MD - Moldavia 2
NG - Nigeria 2
NI - Nicaragua 2
OM - Oman 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SN - Senegal 2
TH - Thailandia 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AU - Australia 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CV - Capo Verde 1
EU - Europa 1
GE - Georgia 1
GY - Guiana 1
IR - Iran 1
KG - Kirghizistan 1
KH - Cambogia 1
KI - Kiribati 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LY - Libia 1
Totale 8.480
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Città #
Ashburn 1.153
San Jose 549
Singapore 456
Hong Kong 421
Dallas 299
Ho Chi Minh City 184
Lauterbourg 132
Beijing 130
The Dalles 127
Hanoi 123
Hefei 122
Chandler 96
Moscow 90
Des Moines 88
Jacksonville 88
Fairfield 80
Los Angeles 74
Dublin 60
Boardman 54
New York 49
Woodbridge 43
Council Bluffs 42
Ancona 41
Buffalo 41
Wilmington 41
São Paulo 40
Houston 34
Seattle 34
Ann Arbor 31
Chicago 30
Haiphong 26
Da Nang 25
Abidjan 23
Rome 23
Helsinki 22
Lawrence 22
Mexico City 22
Princeton 22
Hangzhou 21
Orem 21
San Mateo 21
Cambridge 20
Warsaw 19
Santa Clara 18
Mugnano di Napoli 17
Salt Lake City 17
Rio de Janeiro 16
Atlanta 15
Nuremberg 15
Tashkent 15
Belo Horizonte 14
Boston 14
London 14
Stockholm 14
Brooklyn 13
Baghdad 12
Naples 12
San Diego 12
Denver 11
Tokyo 11
Brasília 10
Montreal 10
Phoenix 10
Biên Hòa 9
Cape Town 9
Manchester 9
Quito 9
Buenos Aires 8
Dhaka 8
Elk Grove Village 8
Johannesburg 8
Nairobi 8
Poplar 8
Vienna 8
Campinas 7
Can Tho 7
Centro 7
Curitiba 7
Frankfurt am Main 7
Jeddah 7
Washington 7
Amman 6
Bogotá 6
Guayaquil 6
Jakarta 6
Mumbai 6
Paris 6
Salvador 6
San Francisco 6
Thái Bình 6
Amsterdam 5
Ankara 5
Bến Tre 5
Casablanca 5
Erbil 5
Kuala Lumpur 5
Lahore 5
Ninh Bình 5
Quận Ba 5
Santo André 5
Totale 5.554
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Nome #
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells. 142
NCX1 is a new rest target gene: Role in cerebral ischemia 128
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels 126
The antiepileptic drug Levetiracetam decreases the IP3-Dependent [Ca2+]i increase induced by ATP and BK in PC12 cells 124
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 120
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum 118
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 116
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 113
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 110
First- and Second-generation H1 antihistamines: from the molecular basis of their interaction with HERG K+ channels to physiological and pathophysiological implication 109
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 105
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 104
Involvement of phosphodiesterase-cGMP-PKG pathway in intracellular Ca2+ oscillations in pituitary GH3 cells 101
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 94
Effects of subtoxic 3-methylmethcathinone concentrations on neuronal cell electrical properties 93
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 92
Sodium nitroprusside prevents chemical hypoxya-induced cell death through iron ions stimulating the activity of the Na+-Ca2+ exchanger in C6 glioma cells. 91
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 85
nNOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 84
Plasma membrane and organellar targets of stim1 for intracellular calcium handling in health and neurodegenerative diseases 82
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 81
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells 81
Pharmacological inhibition of lysosomal two-pore channel 2 (TPC2) confers neuroprotection in stroke via autophagy regulation 80
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 79
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 78
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 77
Nanoparticles encapsulating phosphatidylinositol derivatives promote neuroprotection and functional improvement in preclinical models of ALS via a long-lasting activation of TRPML1 lysosomal channel 77
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage 77
Size-based effects of anthropogenic ultrafine particles on activation of human lung macrophages 76
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death 74
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 74
Cerium-Doped Self-Assembling Nanoparticles as a Novel Anti-Oxidant Delivery System Preserving Mitochondrial Function in Cortical Neurons Exposed to Ischemia-like Conditions 73
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 72
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 72
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 70
The antioxidant activity of limonene counteracts neurotoxicity triggered byaβ1-42 oligomers in primary cortical neurons 70
Ca2 + dysregulation in the pathogenesis of amyotrophic lateral sclerosis 69
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 68
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 68
Involvement of KV3.4 Channel in Parkinson's Disease: A Key Player in the Control of Midbrain and Striatum Differential Vulnerability during Disease Progression? 67
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 67
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 67
Calcium/Calmodulin-Dependent Protein Kinase II and Its Endogenous Inhibitor α in Medullary Thyroid Cancer 66
Profarmaci dell’arginina con elevata attività terapeutica 66
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells 65
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 65
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia 65
Effects of D-aspartate on oligodendrocytes during differentiation, demyelination and remyelination processes 64
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 63
L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson's Disease Models 63
Synthesis and Characterization of Novel Mono- And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult 63
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells 62
SARS-CoV-2 Spike Protein Activates Human Lung Macrophages 62
Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons? 62
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 62
Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis 62
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 61
The Na+/Ca2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia 60
Expanding Structure-Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators 59
Evidence of calcium- and SNARE-dependent release of CuZn superoxide dismutase from rat pituitary GH3 cells and synaptosomes in response to depolarization 59
Nuclear localization of NCX: Role in Ca2+ handling and pathophysiological implications 58
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 58
Size-Based Effects of Anthropogenic Ultrafine Particles on Lysosomal TRPML1 Channel and Autophagy in Motoneuron-like Cells 58
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor 57
Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells 57
Calcium Dyshomeostasis and Lysosomal Ca2+ Dysfunction in Amyotrophic Lateral Sclerosis 57
Gliadin Peptides Induce Tissue Transglutaminase Activation and ER-Stress through Ca(2+) Mobilization in Caco-2 Cells 57
The Cu-Zn superoxide dismutase (SOD1) inhibits ERK phosphorylation by muscarinic receptor modulation in rat pituitary GH3 cells 56
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 56
Na+-Ca2+ Exchanger (NCX3) Knock-Out Mice Display an Impairment in Hippocampal Long-Term Potentiation and Spatial Learning and Memory 56
Peculiar Ca2+ Homeostasis, ER Stress, Autophagy, and TG2 Modulation in Celiac Disease Patient-Derived Cells 56
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 56
The 3-(3-oxoisoindolin-1-yl)pentane-2,4-dione (ISOAC1) as a new molecule able to inhibit Amyloid β aggregation and neurotoxicity 55
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance 55
Taming Microglia in Alzheimer's Disease: Exploring Potential Implications of Choline Alphoscerate via α7 nAChR Modulation 55
Probing the Ca2+ mobilizing properties on primary cortical neurons of a new stable cADPR mimic 55
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 54
Increased KV2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K+ Currents in Hippocampal Neurons of the Tg2576 Alzheimer's Disease Mouse 54
Nitric oxide induces [Ca2+]i oscillations in pituitary GH3 cells: involvement of IDR and ERG K+ currents 54
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage 53
The two isoforms of the Na+/Ca2+ exchanger, NCX1 and NCX3, constitute novel additional targets for the prosurvival action of Akt/protein kinase B pathway 53
Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning 52
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis 52
Exploring the Therapeutic Potential of Phytochemicals in Alzheimer's Disease: Focus on Polyphenols and Monoterpenes 52
NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core 52
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 51
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 51
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia 51
The repressor element 1-silencing transcription factor is a novel molecular target for the neurotoxic effect of the polychlorinated biphenyl mixture aroclor 1254 in neuroblastoma SH-SY5Y cells 50
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 50
Glutamate-independent calcium toxicity: introduction 50
New insights in mitochondrial calcium handling by sodium/calcium exchanger 50
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 50
The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer’s Disease 49
Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells 49
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 49
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 48
The Na+/Ca2+ exchangers in demyelinating diseases 47
Studies on maitotoxin-induced intracellular Ca(2+) elevation in chinese hamster ovary cells stably transfected with cDNAs encoding for L-type Ca(2+) channel subunits 47
Pharmacological blockade of ERG K(+) channels and Ca(2+) influx through store-operated channels exerts opposite effects on intracellular Ca(2+) oscillations in pituitary GH(3) cells 47
Totale 7.000
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Categoria #
all - tutte 30.285
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 30.285
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202197 0 0 0 0 0 0 0 0 0 42 32 23
2021/2022152 12 40 0 12 1 9 6 5 14 9 15 29
2022/2023348 27 23 26 26 23 119 1 18 68 0 9 8
2023/2024153 32 4 10 23 30 23 4 2 1 3 2 19
2024/20251.907 21 36 14 2 9 252 408 73 474 125 196 297
2025/20265.517 242 473 283 387 684 478 1.323 580 566 501 0 0
Totale 8.685