IRIS
SECONDO, Agnese
 Distribuzione geografica
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Continente #
NA - Nord America 2.116
AS - Asia 1.522
EU - Europa 1.057
SA - Sud America 372
AF - Africa 52
OC - Oceania 3
Continente sconosciuto - Info sul continente non disponibili 2
Totale 5.124
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Nazione #
US - Stati Uniti d'America 2.066
SG - Singapore 598
HK - Hong Kong 386
RU - Federazione Russa 380
CN - Cina 329
BR - Brasile 321
IT - Italia 176
SE - Svezia 88
UA - Ucraina 82
VN - Vietnam 72
DE - Germania 60
IE - Irlanda 59
GB - Regno Unito 54
DK - Danimarca 29
TR - Turchia 29
FI - Finlandia 24
MX - Messico 24
FR - Francia 23
NL - Olanda 22
AR - Argentina 21
AT - Austria 20
CI - Costa d'Avorio 20
CA - Canada 19
BD - Bangladesh 18
KR - Corea 17
PL - Polonia 16
ID - Indonesia 11
IN - India 11
ZA - Sudafrica 11
IQ - Iraq 10
JP - Giappone 8
EC - Ecuador 7
ES - Italia 7
MA - Marocco 7
AE - Emirati Arabi Uniti 6
CO - Colombia 5
EG - Egitto 5
LT - Lituania 5
NP - Nepal 5
PK - Pakistan 4
PY - Paraguay 4
SA - Arabia Saudita 4
UZ - Uzbekistan 4
VE - Venezuela 4
BE - Belgio 3
CL - Cile 3
JO - Giordania 3
MY - Malesia 3
UY - Uruguay 3
BO - Bolivia 2
DO - Repubblica Dominicana 2
ET - Etiopia 2
IL - Israele 2
JM - Giamaica 2
MD - Moldavia 2
NG - Nigeria 2
PE - Perù 2
PT - Portogallo 2
TN - Tunisia 2
AL - Albania 1
AU - Australia 1
BY - Bielorussia 1
CR - Costa Rica 1
DZ - Algeria 1
EU - Europa 1
HN - Honduras 1
KE - Kenya 1
KI - Kiribati 1
KZ - Kazakistan 1
LU - Lussemburgo 1
OM - Oman 1
PW - Palau 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
TT - Trinidad e Tobago 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 5.124
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Città #
Hong Kong 385
Ashburn 374
Singapore 332
Dallas 298
Hefei 122
Beijing 101
Chandler 96
Des Moines 88
Jacksonville 88
Fairfield 80
Moscow 79
Los Angeles 64
The Dalles 64
Dublin 59
Boardman 53
Woodbridge 43
Ancona 41
Buffalo 41
New York 41
Wilmington 41
Seattle 34
Ann Arbor 31
Houston 31
Ho Chi Minh City 28
São Paulo 28
Chicago 26
Lawrence 22
Princeton 22
Rome 22
San Mateo 21
Abidjan 20
Cambridge 20
Hangzhou 20
Hanoi 20
Mugnano di Napoli 17
Salt Lake City 17
Nuremberg 14
Warsaw 14
Brooklyn 13
Stockholm 13
London 12
San Diego 12
Atlanta 11
Boston 11
Belo Horizonte 10
Orem 10
Rio de Janeiro 10
Brasília 9
Helsinki 9
Mexico City 9
Montreal 9
Naples 9
Santa Clara 9
Denver 8
Tokyo 8
Vienna 8
Centro 7
Manchester 7
Phoenix 7
Curitiba 6
Johannesburg 6
San Francisco 6
Washington 6
Campinas 5
Jakarta 5
Poplar 5
Santo André 5
Ankara 4
Belpasso 4
Biên Hòa 4
Buenos Aires 4
Cape Town 4
Columbus 4
Dhaka 4
Easley 4
Elk Grove Village 4
Frankfurt am Main 4
Milan 4
Paris 4
Ribeirão das Neves 4
Salvador 4
Secaucus 4
São Bernardo do Campo 4
Tashkent 4
Toronto 4
Amman 3
Amsterdam 3
Auburn Hills 3
Baghdad 3
Blumenau 3
Bologna 3
Cairo 3
Casablanca 3
Charlotte 3
Cincinnati 3
Duque de Caxias 3
Joinville 3
Macerata Feltria 3
Norwalk 3
Quito 3
Totale 3.259
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Nome #
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells. 125
The antiepileptic drug Levetiracetam decreases the IP3-Dependent [Ca2+]i increase induced by ATP and BK in PC12 cells 104
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 101
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels 101
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 100
NCX1 is a new rest target gene: Role in cerebral ischemia 99
First- and Second-generation H1 antihistamines: from the molecular basis of their interaction with HERG K+ channels to physiological and pathophysiological implication 98
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 95
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum 93
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 90
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 87
Involvement of phosphodiesterase-cGMP-PKG pathway in intracellular Ca2+ oscillations in pituitary GH3 cells 86
Sodium nitroprusside prevents chemical hypoxya-induced cell death through iron ions stimulating the activity of the Na+-Ca2+ exchanger in C6 glioma cells. 78
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 77
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 76
Effects of subtoxic 3-methylmethcathinone concentrations on neuronal cell electrical properties 74
nNOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 72
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells 71
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 67
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia 59
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 57
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 57
Pharmacological inhibition of lysosomal two-pore channel 2 (TPC2) confers neuroprotection in stroke via autophagy regulation 54
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage 52
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 52
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death 50
Plasma membrane and organellar targets of stim1 for intracellular calcium handling in health and neurodegenerative diseases 50
Cerium-Doped Self-Assembling Nanoparticles as a Novel Anti-Oxidant Delivery System Preserving Mitochondrial Function in Cortical Neurons Exposed to Ischemia-like Conditions 49
Profarmaci dell’arginina con elevata attività terapeutica 49
Ca2 + dysregulation in the pathogenesis of amyotrophic lateral sclerosis 48
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 46
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 44
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 43
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 41
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 41
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 41
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 41
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 41
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 39
Na+-Ca2+ Exchanger (NCX3) Knock-Out Mice Display an Impairment in Hippocampal Long-Term Potentiation and Spatial Learning and Memory 39
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 39
Effects of D-aspartate on oligodendrocytes during differentiation, demyelination and remyelination processes 39
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells 38
Calcium/Calmodulin-Dependent Protein Kinase II and Its Endogenous Inhibitor α in Medullary Thyroid Cancer 38
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 38
Calcium Dyshomeostasis and Lysosomal Ca2+ Dysfunction in Amyotrophic Lateral Sclerosis 38
The antioxidant activity of limonene counteracts neurotoxicity triggered byaβ1-42 oligomers in primary cortical neurons 38
Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis 38
Synthesis and Characterization of Novel Mono- And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult 38
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells 36
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 36
Nanoparticles encapsulating phosphatidylinositol derivatives promote neuroprotection and functional improvement in preclinical models of ALS via a long-lasting activation of TRPML1 lysosomal channel 36
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 36
Expanding Structure-Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators 35
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 35
Probing the Ca2+ mobilizing properties on primary cortical neurons of a new stable cADPR mimic 35
Involvement of KV3.4 Channel in Parkinson's Disease: A Key Player in the Control of Midbrain and Striatum Differential Vulnerability during Disease Progression? 34
Nuclear localization of NCX: Role in Ca2+ handling and pathophysiological implications 33
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor 33
SARS-CoV-2 Spike Protein Activates Human Lung Macrophages 33
The 3-(3-oxoisoindolin-1-yl)pentane-2,4-dione (ISOAC1) as a new molecule able to inhibit Amyloid β aggregation and neurotoxicity 32
Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons? 32
Size-Based Effects of Anthropogenic Ultrafine Particles on Lysosomal TRPML1 Channel and Autophagy in Motoneuron-like Cells 32
Increased KV2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K+ Currents in Hippocampal Neurons of the Tg2576 Alzheimer's Disease Mouse 32
Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells 32
L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson's Disease Models 31
Size-based effects of anthropogenic ultrafine particles on activation of human lung macrophages 31
Involvement of PI3-K, mitogen-activated protein kinase and PKB in the upregulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor actvation in GH3 cells 30
Gliadin Peptides Induce Tissue Transglutaminase Activation and ER-Stress through Ca(2+) Mobilization in Caco-2 Cells 30
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 30
Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells 29
Evidence of calcium- and SNARE-dependent release of CuZn superoxide dismutase from rat pituitary GH3 cells and synaptosomes in response to depolarization 28
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene 28
Lysosomal Channels as New Molecular Targets in the Pharmacological Therapy of Neurodegenerative Diseases via Autophagy Regulation 28
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 27
The Na+/Ca2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia 27
The Cu-Zn superoxide dismutase (SOD1) inhibits ERK phosphorylation by muscarinic receptor modulation in rat pituitary GH3 cells 26
Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning 26
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 26
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 26
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 26
Taming Microglia in Alzheimer's Disease: Exploring Potential Implications of Choline Alphoscerate via α7 nAChR Modulation 26
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 26
NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core 26
Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40 26
New insights in mitochondrial calcium handling by sodium/calcium exchanger 26
CuZn Superoxide dismutase increases intracellular calcium levels via phospholipase C-protein Kinase C pathway in SK-N-BE cells 26
Nuclear Factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones 26
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 26
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 25
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis 25
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance 25
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage 25
Effects of HIV-1 Tat protein on ion secretion and on cell proliferation in Human intestinal epithelial cells 25
Nitric oxide induces [Ca2+]i oscillations in pituitary GH3 cells: involvement of IDR and ERG K+ currents 25
Genetically modified mice to unravel physiological and pathophysiological roles played by NCX isoforms 24
Exploring the Therapeutic Potential of Phytochemicals in Alzheimer's Disease: Focus on Polyphenols and Monoterpenes 24
Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors. STAIANO and LOFFREDO are CO-FIRST AUTHORS 24
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia 24
TSH/cAMP up-regulate sarco/endoplasmic reticulum Ca2+-ATPases expression and activity in PC Cl3 thyroid cells 23
Totale 4.499
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Categoria #
all - tutte 24.886
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.886
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021179 0 0 0 0 0 10 22 21 29 42 32 23
2021/2022152 12 40 0 12 1 9 6 5 14 9 15 29
2022/2023348 27 23 26 26 23 119 1 18 68 0 9 8
2023/2024153 32 4 10 23 30 23 4 2 1 3 2 19
2024/20251.907 21 36 14 2 9 252 408 73 474 125 196 297
2025/20262.153 242 473 283 387 684 84 0 0 0 0 0 0
Totale 5.321