IRIS
SECONDO, Agnese
 Distribuzione geografica
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Continente #
NA - Nord America 4.842
AS - Asia 2.684
EU - Europa 1.759
SA - Sud America 593
Continente sconosciuto - Info sul continente non disponibili 208
AF - Africa 101
OC - Oceania 3
Totale 10.190
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Nazione #
US - Stati Uniti d'America 4.724
SG - Singapore 858
RU - Federazione Russa 622
VN - Vietnam 557
BR - Brasile 454
CN - Cina 449
HK - Hong Kong 436
IT - Italia 392
FR - Francia 162
SE - Svezia 90
UA - Ucraina 90
BD - Bangladesh 71
GB - Regno Unito 69
DE - Germania 68
IE - Irlanda 62
AR - Argentina 52
MX - Messico 51
IN - India 50
TR - Turchia 41
NL - Olanda 40
FI - Finlandia 39
CA - Canada 35
IQ - Iraq 35
DK - Danimarca 29
EC - Ecuador 28
ZA - Sudafrica 25
PL - Polonia 24
CI - Costa d'Avorio 23
ID - Indonesia 23
AT - Austria 20
KR - Corea 20
CO - Colombia 16
UZ - Uzbekistan 16
JP - Giappone 15
MA - Marocco 15
SA - Arabia Saudita 15
VE - Venezuela 15
ES - Italia 14
PH - Filippine 13
PK - Pakistan 13
AE - Emirati Arabi Uniti 11
KE - Kenya 10
JM - Giamaica 9
MY - Malesia 9
JO - Giordania 8
NP - Nepal 8
LT - Lituania 7
UY - Uruguay 7
CL - Cile 6
HN - Honduras 6
PT - Portogallo 6
PY - Paraguay 6
AZ - Azerbaigian 5
BE - Belgio 5
BO - Bolivia 5
EG - Egitto 5
TN - Tunisia 5
DZ - Algeria 4
IR - Iran 4
KZ - Kazakistan 4
PA - Panama 4
AL - Albania 3
CR - Costa Rica 3
ET - Etiopia 3
GR - Grecia 3
NI - Nicaragua 3
PE - Perù 3
TT - Trinidad e Tobago 3
BG - Bulgaria 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
HU - Ungheria 2
IL - Israele 2
KW - Kuwait 2
MD - Moldavia 2
NG - Nigeria 2
OM - Oman 2
PS - Palestinian Territory 2
RS - Serbia 2
SN - Senegal 2
TH - Thailandia 2
TW - Taiwan 2
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
AU - Australia 1
BS - Bahamas 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CV - Capo Verde 1
EE - Estonia 1
EU - Europa 1
GE - Georgia 1
GY - Guiana 1
HR - Croazia 1
KG - Kirghizistan 1
KH - Cambogia 1
KI - Kiribati 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
Totale 9.972
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Città #
Ashburn 1.337
San Jose 643
Singapore 470
Council Bluffs 459
Hong Kong 428
Dallas 302
Ho Chi Minh City 184
Beijing 141
The Dalles 134
Lauterbourg 132
Hanoi 123
Hefei 122
Chandler 96
Jacksonville 91
Los Angeles 90
Moscow 90
Des Moines 88
Fairfield 80
Dublin 61
Boardman 59
Milan 52
New York 52
Ancona 48
Buffalo 43
Woodbridge 43
Wilmington 41
Santa Clara 40
São Paulo 40
Phoenix 38
Houston 36
Seattle 34
Ann Arbor 31
Chicago 30
Haiphong 26
Da Nang 25
Miano 25
Orem 24
Rome 24
Abidjan 23
Mexico City 23
Helsinki 22
Lawrence 22
Princeton 22
Atlanta 21
Hangzhou 21
San Mateo 21
Cambridge 20
Naples 20
Warsaw 19
Mugnano di Napoli 17
Salt Lake City 17
Boston 16
Rio de Janeiro 16
Nuremberg 15
San Diego 15
Tashkent 15
Belo Horizonte 14
Brooklyn 14
London 14
Montreal 14
Stockholm 14
Denver 13
Baghdad 12
Tokyo 12
Brasília 10
Quito 10
San Francisco 10
Biên Hòa 9
Cape Town 9
Manchester 9
Buenos Aires 8
Can Tho 8
Dhaka 8
Elk Grove Village 8
Frankfurt am Main 8
Johannesburg 8
Nairobi 8
Poplar 8
Vienna 8
Washington 8
Campinas 7
Centro 7
Curitiba 7
Guayaquil 7
Jeddah 7
Shanghai 7
Toronto 7
Amman 6
Bogotá 6
Jakarta 6
Mumbai 6
Paris 6
Salvador 6
Thái Bình 6
Amsterdam 5
Ankara 5
Bến Tre 5
Casablanca 5
Catania 5
Columbus 5
Totale 6.492
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Nome #
Involvement of the nitric oxide/protein kinase G pathway in polychlorinated biphenyl-induced cell death in SH-SY 5Y neuroblastoma cells. 148
'Janus face' of nitric oxide action on plasma membrane and intracellular ionic channels 140
NCX1 is a new rest target gene: Role in cerebral ischemia 135
Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions 130
The antiepileptic drug Levetiracetam decreases the IP3-Dependent [Ca2+]i increase induced by ATP and BK in PC12 cells 130
NCX1 Exchanger Cooperates with Calretinin to Confer Preconditioning-Induced Tolerance Against Cerebral Ischemia in the Striatum 124
Preconditioning, induced by sub-toxic dose of the neurotoxin L-BMAA, delays ALS progression in mice and prevents Na+/Ca2+exchanger 3 downregulation 119
Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt 119
First- and Second-generation H1 antihistamines: from the molecular basis of their interaction with HERG K+ channels to physiological and pathophysiological implication 118
Modulation of ion channels by reactive oxygen and nitrogen species: a pathophysiological role in brain aging? 115
BHK cells transfected with NCX3 are more resistant to hypoxia followed by reoxygenation than those transfected with NCX1 and NCX2: Possible relationship with mitochondrial membrane potential 111
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs). 111
Involvement of phosphodiesterase-cGMP-PKG pathway in intracellular Ca2+ oscillations in pituitary GH3 cells 109
ORAI1/STIM1 Interaction Intervenes in Stroke and in Neuroprotection Induced by Ischemic Preconditioning Through Store-Operated Calcium Entry 109
Genetic Up-Regulation or Pharmacological Activation of the Na+/Ca2+ Exchanger 1 (NCX1) Enhances Hippocampal-Dependent Contextual and Spatial Learning and Memory 108
Nanoparticles encapsulating phosphatidylinositol derivatives promote neuroprotection and functional improvement in preclinical models of ALS via a long-lasting activation of TRPML1 lysosomal channel 103
Effects of subtoxic 3-methylmethcathinone concentrations on neuronal cell electrical properties 101
Na+/Ca2+ exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca2+ regulation during neuronal differentiation 101
Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 101
Pharmacological inhibition of lysosomal two-pore channel 2 (TPC2) confers neuroprotection in stroke via autophagy regulation 99
Sodium nitroprusside prevents chemical hypoxya-induced cell death through iron ions stimulating the activity of the Na+-Ca2+ exchanger in C6 glioma cells. 99
Involvement of PI3'-K, mitogen-activated protein kinase and protein kinase B in the up-regulation of the expression of nNOSalpha and nNOSbeta splicing variants induced by PRL-receptor activation in GH3 cells 97
Plasma membrane and organellar targets of stim1 for intracellular calcium handling in health and neurodegenerative diseases 95
Size-based effects of anthropogenic ultrafine particles on activation of human lung macrophages 94
Calcium/Calmodulin-Dependent Protein Kinase II and Its Endogenous Inhibitor α in Medullary Thyroid Cancer 94
nNOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 91
Involvement of KV3.4 Channel in Parkinson's Disease: A Key Player in the Control of Midbrain and Striatum Differential Vulnerability during Disease Progression? 90
Effects of manidipine and nitrendipine enantiomers on the plateau phase of K+-induced intracellular Ca2+ increase in GH3 cells 87
Evidence of calcium- and SNARE-dependent release of CuZn superoxide dismutase from rat pituitary GH3 cells and synaptosomes in response to depolarization 86
Evidence for a protective role played by Na+-Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats 86
A critical role for the potassium-dependent sodium-calcium exchanger NCKX2 in protection against focal ischemic brain damage 86
Anoxia-induced NF-kappaB-dependent upregulation of NCX1 contributes to Ca2+ refilling into endoplasmic reticulum in cortical neurons 85
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death 85
7-nitro-5-phenyl-1-(pyrrolidin-1-ylmethyl)-1H-benzo[E][1,4]diazepin-2(3H)-one and other benzodiazepine derivatives 84
7-nitro-5-fenil-1(pirrolidin-1-ilmetil)-1H-benzo[e][1,4] diazepin-2(3H)-one ed altri composti derivati delle benzodiazepine 84
The antioxidant activity of limonene counteracts neurotoxicity triggered byaβ1-42 oligomers in primary cortical neurons 84
Critical role of large-conductance calcium- and voltage-activated potassium channels in leptin-induced neuroprotection of N-methyl-d-aspartate-exposed cortical neurons 83
Nitric oxide stimulates NCX1 and NCX2 but inhibits NCX3 isoform by three distinct molecular determinants 83
Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons? 81
Cerium-Doped Self-Assembling Nanoparticles as a Novel Anti-Oxidant Delivery System Preserving Mitochondrial Function in Cortical Neurons Exposed to Ischemia-like Conditions 81
Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in neuronal growth factor (NGF)-induced neuronal differentiation through Ca2+-dependent Akt phosphorylation 81
Endoplasmic reticulum refilling and mitochondrial calcium extrusion promoted in neurons by NCX1 and NCX3 in ischemic preconditioning are determinant for neuroprotection 80
Resveratrol via sirtuin-1 downregulates RE1-silencing transcription factor (REST) expression preventing PCB-95-induced neuronal cell death 78
Effects of D-aspartate on oligodendrocytes during differentiation, demyelination and remyelination processes 77
Cigarette Smoke Condensate Causes a Decrease of the Gene Expression of Cu-Zn Superoxide Dismutase, Mn Superoxide Dismutase, Glutathione Peroxidase, Catalase, and Free Radical-Induced Cell Injury in SH-SY5Y Human Neuroblastoma Cells 76
ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca(2+)/Akt/ERK1/2 prosurvival pathway 76
Ca2 + dysregulation in the pathogenesis of amyotrophic lateral sclerosis 76
SARS-CoV-2 Spike Protein Activates Human Lung Macrophages 75
Genetically modified mice as a strategy to unravel the role played by the na(+)/ca (2+) exchanger in brain ischemia and in spatial learning and memory deficits 75
A New Cell-penetrating Peptide That Blocks the Autoinhibitory XIP Domain of NCX1 and Enhances Antiporter Activity 75
Taming Microglia in Alzheimer's Disease: Exploring Potential Implications of Choline Alphoscerate via α7 nAChR Modulation 75
Activation of pre-synaptic M-type K+ channels inhibits [3H]D-aspartate release by reducing Ca2+ entry through P/Q-type voltage-gated Ca2+ channels 73
Pioglitazone improves mitochondrial organization and bioenergetics in down syndrome cells 72
Cu,Zn superoxide dismutase increases intracellular calcium levels via a phospholipase C-protein kinase C pathway in SK-N-BE neuroblastoma cells 72
NCX1 Expression and Functional Activity Increase in Microglia Invading the Infarct Core 71
Profarmaci dell’arginina con elevata attività terapeutica 71
ERK1/2, p38, and JNK regulate the expression and the activity of the three isoforms of the Na(+) /Ca(2+) exchanger, NCX1, NCX2, and NCX3, in neuronal PC12 cells 70
Na+/Ca2+ exchanger in Na+ efflux-Ca2+ influx mode of operation exerts a neuroprotective role in cellular models of in vitro anoxia and in vivo cerebral ischemia 70
Nuclear localization of NCX: Role in Ca2+ handling and pathophysiological implications 69
Molecular pharmacology of the amiloride analog 3-amino-6-chloro-5-[(4-chloro-benzyl)amino]-n-[[(2,4-dimethylbenzyl)-amino]iminomethyl]-pyrazinecarboxamide (CB-DMB) as a pan inhibitor of the Na+-Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in stably transfected cells 69
L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson's Disease Models 69
Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells 69
Histamine induces exocytosis and IL-6 production from human lung macrophages through interaction with H1 receptors 69
The Cu-Zn superoxide dismutase (SOD1) inhibits ERK phosphorylation by muscarinic receptor modulation in rat pituitary GH3 cells 68
Identification and characterization of the promoter and transcription factors regulating the expression of cerebral sodium/calcium exchanger 2 (NCX2) gene 68
Peculiar Ca2+ Homeostasis, ER Stress, Autophagy, and TG2 Modulation in Celiac Disease Patient-Derived Cells 68
The Na+/Ca2+ Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia 68
Pharmacological characterization of the newly synthesized 5-amino-N-butyl-2-(4-ethoxyphenoxy)-benzamide hydrochloride (BED) as a potent NCX3 inhibitor that worsens anoxic injury in cortical neurons, organotypic hippocampal cultures, and ischemic brain 68
Expanding Structure-Activity Relationships of Human Urotensin II Peptide Analogues: A Proposed Key Role of the N-Terminal Region for Novel Urotensin II Receptor Modulators 67
Size-Based Effects of Anthropogenic Ultrafine Particles on Lysosomal TRPML1 Channel and Autophagy in Motoneuron-like Cells 67
The two isoforms of the Na+/Ca2+ exchanger, NCX1 and NCX3, constitute novel additional targets for the prosurvival action of Akt/protein kinase B pathway 67
Exploring the Therapeutic Potential of Phytochemicals in Alzheimer's Disease: Focus on Polyphenols and Monoterpenes 67
Increased KV2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K+ Currents in Hippocampal Neurons of the Tg2576 Alzheimer's Disease Mouse 66
Calcium Dyshomeostasis and Lysosomal Ca2+ Dysfunction in Amyotrophic Lateral Sclerosis 66
Gliadin Peptides Induce Tissue Transglutaminase Activation and ER-Stress through Ca(2+) Mobilization in Caco-2 Cells 66
Anti-tissue transglutaminase antibodies activate intracellular tissue transglutaminase by modulating cytosolic Ca2+ homeostasis 66
Differentiation of monocytes into macrophages induces the upregulation of histamine H1 receptor 65
Na+-Ca2+ Exchanger (NCX3) Knock-Out Mice Display an Impairment in Hippocampal Long-Term Potentiation and Spatial Learning and Memory 64
Nitric oxide induces [Ca2+]i oscillations in pituitary GH3 cells: involvement of IDR and ERG K+ currents 64
Synthesis and Characterization of Novel Mono- And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult 64
Neuronal NOS activation during oxygen and glucose deprivation triggers cerebellar granule cell death in the later reoxygenation phase 63
Glatiramer Acetate modulates ion channels expression and calcium homeostasis in B cell of patients with relapsing-remitting multiple sclerosis 62
Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning 61
The 3-(3-oxoisoindolin-1-yl)pentane-2,4-dione (ISOAC1) as a new molecule able to inhibit Amyloid β aggregation and neurotoxicity 61
Human trisomic ipscs from down syndrome fibroblasts manifest mitochondrial alterations early during neuronal differentiation 61
Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage 61
The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer’s Disease 61
Prolonged NCX activation prevents SOD1 accumulation, reduces neuroinflammation, ameliorates motor behavior and prolongs survival in a ALS mouse model 61
Neurounina-1, a Novel Compound that Increases Na+/Ca2+ Exchanger Activity, Effectively Protects Against Stroke Damage 61
Probing the Ca2+ mobilizing properties on primary cortical neurons of a new stable cADPR mimic 61
D-Aspartate treatment attenuates myelin damage and stimulates myelin repair 59
Synthesis of cyclic N1-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells 59
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance 59
ncx1, ncx2, and ncx3 gene product expression and function in neuronal anoxia and brain ischemia 59
The repressor element 1-silencing transcription factor is a novel molecular target for the neurotoxic effect of the polychlorinated biphenyl mixture aroclor 1254 in neuroblastoma SH-SY5Y cells 58
Studies on maitotoxin-induced intracellular Ca(2+) elevation in chinese hamster ovary cells stably transfected with cDNAs encoding for L-type Ca(2+) channel subunits 58
Glutamate-independent calcium toxicity: introduction 58
Sorcin induces a drug-resistant phenotype in human colorectal cancer through the modulation of Ca2+ homeostasis 57
Polychlorinated Biphenyls Induce Mitochondrial Dysfunction in SH-SY5Y Neuroblastoma Cells 57
The Na+/Ca2+ exchanger isoform 3 (NCX3) but not isoform 2 (NCX2) and 1 (NCX1) singly transfected in BHK cells plays a protective role in a model of in vitro hypoxia 56
Totale 8.096
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Categoria #
all - tutte 39.484
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.484
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022100 0 0 0 12 1 9 6 5 14 9 15 29
2022/2023348 27 23 26 26 23 119 1 18 68 0 9 8
2023/2024153 32 4 10 23 30 23 4 2 1 3 2 19
2024/20251.907 21 36 14 2 9 252 408 73 474 125 196 297
2025/20266.097 242 473 283 387 684 478 1.323 580 566 599 195 287
2026/2027925 321 265 264 75 0 0 0 0 0 0 0 0
Totale 10.190