IRIS
SORCI, Leonardo
 Distribuzione geografica
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Continente #
NA - Nord America 4.824
AS - Asia 2.670
EU - Europa 2.604
SA - Sud America 621
AF - Africa 161
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
Totale 10.889
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Nazione #
US - Stati Uniti d'America 4.722
SG - Singapore 796
IT - Italia 723
VN - Vietnam 637
CN - Cina 572
BR - Brasile 453
DE - Germania 391
RU - Federazione Russa 350
UA - Ucraina 269
IE - Irlanda 173
FR - Francia 162
HK - Hong Kong 162
SE - Svezia 143
DK - Danimarca 94
TR - Turchia 93
BD - Bangladesh 91
GB - Regno Unito 87
FI - Finlandia 84
KR - Corea 62
VE - Venezuela 55
IQ - Iraq 46
MX - Messico 43
AR - Argentina 41
IN - India 40
SN - Senegal 38
CI - Costa d'Avorio 37
CA - Canada 36
ZA - Sudafrica 27
NL - Olanda 26
EC - Ecuador 24
PK - Pakistan 24
PL - Polonia 24
AT - Austria 23
CO - Colombia 19
ID - Indonesia 19
JP - Giappone 17
PH - Filippine 17
UZ - Uzbekistan 16
BE - Belgio 13
DZ - Algeria 13
MA - Marocco 13
ES - Italia 10
AE - Emirati Arabi Uniti 9
EG - Egitto 8
PE - Perù 8
PY - Paraguay 8
TH - Thailandia 8
CL - Cile 7
JO - Giordania 7
SA - Arabia Saudita 7
SV - El Salvador 7
TN - Tunisia 6
AZ - Azerbaigian 5
KE - Kenya 5
PT - Portogallo 5
TW - Taiwan 5
EU - Europa 4
LT - Lituania 4
MY - Malesia 4
NG - Nigeria 4
OM - Oman 4
RO - Romania 4
AL - Albania 3
BO - Bolivia 3
BY - Bielorussia 3
ET - Etiopia 3
GE - Georgia 3
GT - Guatemala 3
IL - Israele 3
KZ - Kazakistan 3
NI - Nicaragua 3
NP - Nepal 3
UY - Uruguay 3
AU - Australia 2
BG - Bulgaria 2
BH - Bahrain 2
CR - Costa Rica 2
GR - Grecia 2
HN - Honduras 2
IR - Iran 2
IS - Islanda 2
KH - Cambogia 2
KW - Kuwait 2
LB - Libano 2
PA - Panama 2
PS - Palestinian Territory 2
RS - Serbia 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BW - Botswana 1
CH - Svizzera 1
CM - Camerun 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GA - Gabon 1
HR - Croazia 1
IM - Isola di Man 1
JM - Giamaica 1
KG - Kirghizistan 1
Totale 10.878
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Città #
Ashburn 818
Singapore 489
Dallas 407
Jacksonville 277
Chandler 264
Fairfield 258
New York 220
San Jose 208
Ho Chi Minh City 207
Dublin 171
Marche 162
Hong Kong 159
Wilmington 156
Boardman 140
Hanoi 133
Beijing 129
Houston 118
Woodbridge 117
Seattle 101
Milan 100
Los Angeles 94
Ann Arbor 91
The Dalles 88
Ancona 87
Des Moines 86
Cambridge 81
Lauterbourg 64
Lawrence 60
Princeton 60
San Mateo 59
Centro 54
Moscow 48
Munich 44
Caracas 40
Hefei 39
Dakar 38
Abidjan 37
Da Nang 33
São Paulo 32
Orem 30
Council Bluffs 26
San Diego 26
San Francisco 26
Brooklyn 25
Haiphong 24
Baghdad 23
Helsinki 23
Denver 22
London 22
Warsaw 22
Buffalo 21
Aversa 20
Phoenix 20
Guangzhou 19
Rio de Janeiro 19
Atlanta 18
Carpentras 18
Chicago 18
Santa Clara 16
Rome 15
Tokyo 15
Nuremberg 14
Shanghai 14
Tashkent 14
Vienna 14
Boston 13
Porto Alegre 13
Scarlino 13
Washington 13
Brussels 12
Johannesburg 12
Ponte A Égola 12
Turku 12
Dong Ket 11
Ogden 11
Can Tho 10
Hải Dương 10
Kazan' 10
León 10
Montreal 10
Poplar 10
Turin 10
Amsterdam 9
Belo Horizonte 9
Civitanova Marche 9
Columbus 9
Paris 9
Quito 9
Lahore 8
Naples 8
Pune 8
Secaucus 8
Ascoli Piceno 7
Dhaka 7
Frankfurt am Main 7
Medellín 7
Mexico City 7
Ninh Bình 7
Nonantola 7
Salvador 7
Totale 6.627
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Nome #
Eubacterial pyridine nucleotide cycle: identification and characterization of the 'orphan enzyme' nmn deamidase 561
Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival 421
THE DIFFERENTIAL BIOCHEMICAL PROPERTIES OF NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE ISOZYMES ENABLE TO DETERMINE THEIR RELATIVE EXPRESSION LEVELS 319
Genomics-Guided Analysis of NAD Recycling Yields Functional Elucidation of COG1058 as a New Family of Pyrophosphatases 241
Diverse biological effects of the essential oil from Iranian Trachyspermum ammi 221
Molecular insights into the interaction between human nicotinamide phosphoribosyltransferase and Toll-like receptor 4 205
Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC 193
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues 189
Biological Activities of the Essential Oil from Erigeron floribundus 189
FL30: an epidermal growth factor kinase inhibitor overcoming T790M and C797S mutations through unique conformational modulation mechanism 184
Functional characterization of COG1713 (YqeK) as a novel diadenosine tetraphosphate hydrolase family 184
A circulating NAD biosynthetic enzyme is a novel modulator of inflammation 182
Mexican sunflower (Tithonia diversifolia, Asteraceae) volatile oil as a selective inhibitor of Staphylococcus aureus nicotinate mononucleotide adenylyltransferase (NadD) 178
Genomics-driven reconstruction of Acinetobacter NAD metabolism: insights for antibacterial target selection 173
A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase 172
Enzymology of extracellular NAD metabolism 166
Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement 166
Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells 165
Novel assay identifies Nicotinamide riboside, the form of vitamin B3 that boosts metabolism, as a constituent of milk at levels comparable to Niacin 162
Synthesis and degradation of adenosine 5’-tetraphosphate by Nicotinamide and Nicotinate phosphoribosyltransferases 160
Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases. 159
Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators 158
Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism. 158
Exosome and microvesicle miRNAs belong to the pro-inflammatory secretome of senescent endothelial cells 153
Human extracellular NAMPT and NAPRT mediate the inflammatory response through TLR4-binding: molecular insights into the mechanism of interaction 153
Identification of a novel human nicotinamide mononucleotide adenylyltransferase 152
Quinolinate salvage and insights for targeting NAD biosynthesis in group A Streptococci. 152
Bacterial NadQ (COG4111) is a Nudix-like, ATP-responsive regulator of NAD biosynthesis 151
Mycobacterial Nicotinate Mononucleotide Adenylyltransferase: STRUCTURE, MECHANISM, AND IMPLICATIONS FOR DRUG DISCOVERY 149
Bioinformatics and comparative genomics unveil an evolutionary conserved phage NAD metabolism 149
Characterization of Mycobacterium tuberculosis NAD kinase: functional analysis of the full-length enzyme by site-directed mutagenesis. 144
Probing conformational dynamics of EGFR mutants via SEIRA spectroscopy: potential implications for tyrosine kinase inhibitor design 142
Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation 141
Synthesis and biological evaluation of NAD analogs as human pyridine nucleotide adenylyltransferase inhibitors. 141
Nicotinamide mononucleotide synthetase is the key enzyme for an alternative route of NAD biosynthesis in Francisella tularensis. 140
Biosintesi del NAD in Mycobacterium tubercolosis: clonaggio ed espressione dei geni nadD e nadR. 139
Glutamine versus Ammonia Utilization in the NAD Synthetase Family. 139
Glutamate exposure of cortical neurons evokes initial oxidation of NADPH in mitochondria followed by a delayed oxidation of NADH: Delayed redox and calcium deregulation 137
Genomics and Enzymology of NAD Biosynthesis 136
Characterization of the NAD biosynthesis in Francisella tularensis 135
Nicotinate phosphoribosyltransferase: a novel antiinfective target? 133
Metabolic and Bactericidal Effects of Targeted Suppression of NadD and NadE Enzymes in Mycobacteria 132
Identification of Nicotinamide Mononucleotide Deamidase of the Bacterial Pyridine Nucleotide Cycle Reveals a Novel Broadly Conserved Amidohydrolase Family 132
Evolutionary and Comparative Genome Analysis of Phage NAD Metabolic Genes 131
Characterization of the cytokine-like properties of extracellular nicotinamide phosphoribosyltransferase 129
Structural requirements for the interaction of the enzyme nicotinamide phosphoribosyltransferase with Toll-like receptor 4 127
Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD 127
Clonaggio ed espressione di geni da Mycobacterium tuberculosis coinvolti nella sintesi del NAD. 125
NAD biosynthesis enzymes from the bacterial world as valuable tools for vitamin B3 mononucleotides quantitation in mammals 124
Ammonia is the Physiological Substrate of ‘GAT-less’ Prokaryotic NAD Synthetase 123
Transcriptional regulation of NAD metabolism in bacteria: genomic reconstruction of NiaR (YrxA) regulon 121
The Prospective Synergy of Antitubercular Drugs With NAD Biosynthesis Inhibitors 120
Mechanistic insight toward EGFR activation induced by ATP: role of mutations and water in ATP binding patterns 117
NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration. 117
Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase 117
Targeting NAD biosynthesis in bacterial pathogens. Structure-Based development of Inhibitors of Nicotinate Mononucleotide Adenylyltransferase NadD 114
Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. 113
NAD homeostasis in the bacterial response to DNA/RNA damage. 112
Regulation of host immune responses to Schistosoma mansoni by the inhibition of the parasitic NAD salvage pathway 111
The interaction between human NAMPT and NAPRT with TLR4: a focus on the molecular determinants 109
A novel route of NAD synthesis is uncovered in Francisella tularensis 109
Functions of the shared N-terminus of slow wallerian degeneration (WldS) and Ube4b proteins: a sequence required for axon protection and ubiquitination 106
NAD biosynthesis under attack 106
Cloning and characterization of a new human NMN adenylyltransferase. 105
Periplasmic binding proteins Bug69 and Bug27 from Bordetella pertussis are in vitro high-affinity quinolinate binders with a potential role in NAD biosynthesis 104
Una nuova NMN adeniltrasferasi umana: clonaggio, espressione eterologa e caratterizzazione della proteina KIAA0479. 101
NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer 101
S. pyogenes is reliant on salvage of host pyridine precursors for NAD synthesis: implications for pathogenesis and antibacterial intervention 96
Mycobacterium tuberculosis NAD (P) BIOSYNTHETIC ENZYMES AS NOVEL ANTIMICROBIAL DRUG TARGETS 93
Structural biology of NAD metabolism in bacteria 87
Synthesis, Biological, and Computational Evaluations of Conformationally Restricted NAD-Mimics as Discriminant Inhibitors of Human NMN-Adenylyltransferase Isozymes 86
The enzyme NMN deamidase of the bacterial pyridine nucleotide cycle is a novel, broadly conserved amidohydrolase 77
Mycobacterial tuberculosis NadD, a promise for targeting latent and drug-resistant tuberculosis 75
NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment 34
Arabidopsis thaliana nicotinate mononucleotide adenylyltransferase: unveiling the molecular determinants and evolutionary origin of nicotinic acid mononucleotide recognition 34
Totale 11.107
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Categoria #
all - tutte 47.179
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.179
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202146 0 0 0 0 0 0 0 0 0 0 0 46
2021/2022470 23 128 6 11 14 19 24 18 35 45 58 89
2022/20231.005 77 91 64 81 67 150 2 70 239 12 110 42
2023/2024716 105 14 64 74 83 196 15 16 13 26 3 107
2024/20251.502 102 95 78 245 35 41 106 95 267 78 138 222
2025/20265.132 345 286 418 445 507 278 701 603 399 451 583 116
Totale 11.107