Carrier status of the fetus for factor V polymorphism or double homozygosity for mutant alleles of the PAI-1 4 G/4 G and MTHFR T677 T polymorphisms must be considered risk factors for intrauterine fetal death. The clinical implications of these data need to be addressed in a prospective study to confirm our preliminary data and to answer the question of whether or not double homozygous individuals should be treated with low molecular-weight heparin and/or low-dose aspirin.
Unexplained fetal loss: the fetal side of thrombophilia / Tranquilli, Andrea Luigi; Saccucci, Franca; Giannubilo, Stefano Raffaele; Cecati, Monia; Nocchi, Linda; Lorenzi, Sara; Emanuelli, Monica. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - STAMPA. - 94:1(2010), pp. 378-380.
Unexplained fetal loss: the fetal side of thrombophilia.
TRANQUILLI, Andrea Luigi;SACCUCCI, FRANCA;GIANNUBILO, Stefano Raffaele;CECATI, Monia;NOCCHI, LINDA;LORENZI, SARA;EMANUELLI, Monica
2010-01-01
Abstract
Carrier status of the fetus for factor V polymorphism or double homozygosity for mutant alleles of the PAI-1 4 G/4 G and MTHFR T677 T polymorphisms must be considered risk factors for intrauterine fetal death. The clinical implications of these data need to be addressed in a prospective study to confirm our preliminary data and to answer the question of whether or not double homozygous individuals should be treated with low molecular-weight heparin and/or low-dose aspirin.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
