Carrier status of the fetus for factor V polymorphism or double homozygosity for mutant alleles of the PAI-1 4 G/4 G and MTHFR T677 T polymorphisms must be considered risk factors for intrauterine fetal death. The clinical implications of these data need to be addressed in a prospective study to confirm our preliminary data and to answer the question of whether or not double homozygous individuals should be treated with low molecular-weight heparin and/or low-dose aspirin.

Unexplained fetal loss: the fetal side of thrombophilia.

TRANQUILLI, Andrea Luigi;SACCUCCI, FRANCA;GIANNUBILO, Stefano Raffaele;CECATI, Monia;NOCCHI, LINDA;LORENZI, SARA;EMANUELLI, Monica
2010

Abstract

Carrier status of the fetus for factor V polymorphism or double homozygosity for mutant alleles of the PAI-1 4 G/4 G and MTHFR T677 T polymorphisms must be considered risk factors for intrauterine fetal death. The clinical implications of these data need to be addressed in a prospective study to confirm our preliminary data and to answer the question of whether or not double homozygous individuals should be treated with low molecular-weight heparin and/or low-dose aspirin.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11566/50186
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