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How to improve the identification of patients with cancer eligible for genetic counselling?

Objective: International guidelines recommend genetic counselling and if indicated the genetic testing for treatment, disease prevention and follow-up for patients and their relatives. However, there is limited utilisation of genetic counselling. This study aimed to verify whether an individual semi-structured guideline-based interview improves the identification of patients eligible for genetic counselling. Methods: Unselected patients with cancer were interviewed. A dedicated nurs...

Nutations in growing plant shoots: The role of elastic deformations due to gravity loading

The effect of elastic deformations induced by gravity loading on the active circumnutation movements of growing plant shoots is investigated. We consider first a discrete model (a gravitropic spring-pendulum system) and then a continuous rod model which is analyzed both analytically (under the assumption of small deformations) and numerically (in the large deformation regime). We find that, for a choice of material parameters consistent with values reported in the available literature on plan...

MicroMotility: State of the art, recent accomplishments and perspectives on the mathematical modeling of bio-motility at microscopic scales

Mathematical modeling and quantitative study of biological motility (in particular, of motility at microscopic scales) is producing new biophysical insight and is offering opportunities for new discoveries at the level of both fundamental science and technology. These range from the explanation of how complex behavior at the level of a single organism emerges from body architecture, to the understanding of collective phenomena in groups of organisms and tissues, and of how these forms of swar...

Risk Analysis per il controllo delle IOS: epidemiologia dei patogeni sentinella nelle strutture socio-sanitarie della Regione Marche

Introduction. As a part of a project funded by the Italian Center for Disease Control (CCM), a multimodal study with the overall objective of reducing the circulation of alert organisms and describing their epidemiology, was carried out. Methodology. The study was conducted in the Marche Region, with the AOU United Hospitals of Ancona, Polytechnic University of Marche as the coordinating center, with the provision of several stages, as follows: a. establishment of the regional surveillance ne...

Peristaltic waves as optimal gaits in metameric bio-inspired robots

Peristalsis, i.e., a motion pattern arising from the propagation of muscle contraction and expansion waves along the body, is a common locomotion strategy for limbless animals. Mimicking peristalsis in bio-inspired robots has attracted considerable attention in the literature. It has recently been observed that maximal velocity in a metameric earthworm-like robot is achieved by actuating the segments using a "phase coordination" principle. This paper shows that, in fact, peristalsis (which re...

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