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Sensitivity and specificity of in vivo COVID-19 screening by detection dogs: Results of the C19-Screendog multicenter study

: Trained dogs can recognize the volatile organic compounds contained in biological samples of patients with COVID-19 infection. We assessed the sensitivity and specificity of in vivo SARS-CoV-2 screening by trained dogs. We recruited five dog-handler dyads. In the operant conditioning phase, the dogs were taught to distinguish between positive and negative sweat samples collected from volunteers' underarms in polymeric tubes. The conditioning was validated by tests involving 16 positive and ...

Co-location of the oxazolidinone resistance poxtA2 and cfr(D) genes on a multiresistance plasmid from a porcine Streptococcus dysgalactiae subsp. equisimilis, Italy

A cytokine-induced spheroid-based in vitro model for studying osteoarthritis pathogenesis

: Given the lack of in vitro models faithfully reproducing the osteoarthritis (OA) disease on-set, this work aimed at manufacturing a reliable and predictive in vitro cytokine-based Articular Cartilage (AC) model to study OA progression. Cell spheroids of primary human fetal chondrocytes (FCs) and h-TERT mesenchymal stem cells differentiated chondrocytes (Y201-C) were analysed in terms of growth kinetics, cells proliferation and apoptosis over 10 days of culture, in healthy condition or in pr...

Real-world efficacy and safety of luspatercept and predictive factors of response in patients with lower risk myelodysplastic syndromes with ring sideroblasts

Identification of Compact Equivalent Circuit Model for Metamaterial Structures

In this work, a simple and efficient circuit modelling of metamaterial structures, providing a compact circuit able to describe accurately the device over a large bandwidth of operation is proposed. The equivalent circuit model is obtained by the identification process of the load in terms of shunt branches constituted by reactive elements that can be both positive and negative. The circuit model is validated by analysing the Split Ring Resonator (SRR) structure. The presence of negative elem...

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