Recently, acomplete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentialy composed of two main polysaccharides: chondroitin sulfate (60-70%) and heparin (30-40%). Moreover, considerable variations of glycosaminoglycans concentration were found during the first month of lactation, the highest values being present in colostrum compared to mature milk. Metabolism and potential biological functions of human milk glycosaminoglycans are hypothesized and future studies are encouraged.
Human milk glycosaminoglycans: the state of the art and future perspectives / Giovanni Valentino, Coppa; Gabrielli, Orazio; Enrico, Bertino; Zampini, Lucia; Galeazzi, Tiziana; Lucia, Padella; Lucia, Santoro; Rita Lucia, Marchesiello; Fabio, Galeotti; Francesca, Maccari; Nicola, Volpi. - In: THE ITALIAN JOURNAL OF PEDIATRICS. - ISSN 1824-7288. - STAMPA. - 39:(2013), p. 2. [10.1186/1824-7288-39-2]
Human milk glycosaminoglycans: the state of the art and future perspectives
GABRIELLI, ORAZIO;ZAMPINI, LUCIA;GALEAZZI, Tiziana;
2013-01-01
Abstract
Recently, acomplete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentialy composed of two main polysaccharides: chondroitin sulfate (60-70%) and heparin (30-40%). Moreover, considerable variations of glycosaminoglycans concentration were found during the first month of lactation, the highest values being present in colostrum compared to mature milk. Metabolism and potential biological functions of human milk glycosaminoglycans are hypothesized and future studies are encouraged.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
