BACKGROUND: The macroscopic structure of bone has been traditionally studied through x-ray radiography or x-ray tomography. However, the resolution limits of these techniques do not enable the reconstruction of the composite bone architecture at the nanometer level. Compared with histomorphometry, x-ray micro-CT has shown its efficiency in providing nondestructive and rapid 3D images and measurements on bone microstructure. Micro-CT higher resolution has been achieved with synchrotron radiation-based computed microtomography (SRμCT). PURPOSE: The aim of this study was a histological and SRμCT analysis of 2 porous titanium implants. MATERIALS AND METHODS: Two direct laser metal forming titanium implants were inserted in the posterior maxilla of a patient and retrieved after 2 months. One of these implants was treated to obtain thin ground sections, whereas the other underwent a SRμCT evaluation. RESULTS: The histological results, showing that the implant surface presented superficial debris and particle inclusions in the surrounding tissue close to the bone area, were confirmed by micro-CT investigations. CONCLUSIONS: SRμCT allowed high resolution with good sample penetration and depth of focus and an evaluation of the relative arrangement of structures that cannot be determined by 2D imaging.
Histological and Synchrotron Radiation-Based Computed Microtomography Study of 2 Human-Retrieved Direct Laser Metal Formed Titanium Implants / Carlo, Mangano; Adriano, Piattelli; Francesco, Mangano; Rustichelli, Franco; Jamil Awad, Shibli; Giovanna, Iezzi; Giuliani, Alessandra. - In: IMPLANT DENTISTRY. - ISSN 1056-6163. - 22:2(2013), pp. 175-181. [10.1097/ID.0b013e318282817d.]
Histological and Synchrotron Radiation-Based Computed Microtomography Study of 2 Human-Retrieved Direct Laser Metal Formed Titanium Implants
RUSTICHELLI, Franco;GIULIANI, ALESSANDRA
2013-01-01
Abstract
BACKGROUND: The macroscopic structure of bone has been traditionally studied through x-ray radiography or x-ray tomography. However, the resolution limits of these techniques do not enable the reconstruction of the composite bone architecture at the nanometer level. Compared with histomorphometry, x-ray micro-CT has shown its efficiency in providing nondestructive and rapid 3D images and measurements on bone microstructure. Micro-CT higher resolution has been achieved with synchrotron radiation-based computed microtomography (SRμCT). PURPOSE: The aim of this study was a histological and SRμCT analysis of 2 porous titanium implants. MATERIALS AND METHODS: Two direct laser metal forming titanium implants were inserted in the posterior maxilla of a patient and retrieved after 2 months. One of these implants was treated to obtain thin ground sections, whereas the other underwent a SRμCT evaluation. RESULTS: The histological results, showing that the implant surface presented superficial debris and particle inclusions in the surrounding tissue close to the bone area, were confirmed by micro-CT investigations. CONCLUSIONS: SRμCT allowed high resolution with good sample penetration and depth of focus and an evaluation of the relative arrangement of structures that cannot be determined by 2D imaging.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.