NAD kinase is an essential enzyme, which plays a key role in cellular energy and signal transduction systems. In this report, the recent studies on the features of bacterial and human NAD kinases are summarized. They include detailed kinetic and structural analyses and highlight important differences, which could be exploited for the design of novel selective antimicrobial drugs.
Structural and functional properties of NAD kinase, a key enzyme in NADP biosynthesis / Magni, Giulio; Orsomando, Giuseppe; Raffaelli, Nadia. - In: MINI-REVIEWS IN MEDICINAL CHEMISTRY. - ISSN 1389-5575. - STAMPA. - 6:7(2006), pp. 739-746. [10.2174/138955706777698688]
Structural and functional properties of NAD kinase, a key enzyme in NADP biosynthesis.
MAGNI, GIULIO;ORSOMANDO, Giuseppe;RAFFAELLI, Nadia
2006-01-01
Abstract
NAD kinase is an essential enzyme, which plays a key role in cellular energy and signal transduction systems. In this report, the recent studies on the features of bacterial and human NAD kinases are summarized. They include detailed kinetic and structural analyses and highlight important differences, which could be exploited for the design of novel selective antimicrobial drugs.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
