Cerebrovascular assessment for the risk prediction of Alzheimer’s disease.

Cerebrovascular Assessment for the Risk Prediction of Alzheimer's Disease. Silvestrini M, Viticchi G, Altamura C, Luzzi S, Balucani C, Vernieri F. Neurological Clinic, Marche Polytechnic University, Ancona, Italy. Increasing evidence is emerging that vascular disease and its risk factors play a role in the development of Alzheimer's disease (AD) and affect the probability of an adverse outcome. The aims of this review are to explore the relationship between vascular risk factors and AD and to discuss the potential use of vascular markers in the clinical approach to cognitive impairment. Moreover, we present evidence about the potential use of ultrasonographic and neuroradiologic markers of cognitive impairment in order to establish possible treatment strategies in subjects with a clinical profile at risk of developing AD.