In order to achieve the most satisfactory results in tissue expansion, a cream containing human recombinant epidermal growth factor (EGF) was applied daily to the expanding skin. The capacity of EGF to stimulate tissue repair has been evaluated on expanded skin flaps, comparing surgical procedures carried out with and without EGF. The present clinical, morphological, immunohistochemical and morphometric results demonstrate that EGF used together with the tissue expander may improve skin repair after mechanical stretching.

Tissue expansion improvement: The role of epidermal growth factor / G., Ricotti; M. M., Tappa; M. G., Tucci; Pugnaloni, Armanda; Lucarini, Guendalina; G., Biagini; A., Bertani; E., Toschi; C., Castaldini. - In: JOURNAL OF MATERIALS SCIENCE. MATERIALS IN MEDICINE. - ISSN 0957-4530. - STAMPA. - 4:4(1993), pp. 345-352. [10.1007/BF00122192]

Tissue expansion improvement: The role of epidermal growth factor

PUGNALONI, Armanda;LUCARINI, Guendalina;
1993-01-01

Abstract

In order to achieve the most satisfactory results in tissue expansion, a cream containing human recombinant epidermal growth factor (EGF) was applied daily to the expanding skin. The capacity of EGF to stimulate tissue repair has been evaluated on expanded skin flaps, comparing surgical procedures carried out with and without EGF. The present clinical, morphological, immunohistochemical and morphometric results demonstrate that EGF used together with the tissue expander may improve skin repair after mechanical stretching.
1993
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11566/75207
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