The in vitro activity of citropin 1.1 against gram-positive cocci was measured by MIC, minimal bactericidal concentration, time-kill studies, and a checkerboard titration method. Streptococci and staphylococci were inhibited at concentrations between 1 and 16 mg/liter, respectively. Enterococci showed less susceptibility. Synergy was demonstrated when citropin 1.1 was combined with clarithromycin and doxycycline.
In vitro activity and killing effect of citropin 1.1 against gram-positive pathogens causing skin and soft tissue infections / Giacometti, Andrea; Cirioni, Oscar; Kamysz, W; Silvestri, Carmela; Del Prete, Ms; Licci, Alberto; D'Amato, G; Łukasiak, J; Scalise, Giorgio. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - STAMPA. - 49:6(2005), pp. 2507-2509. [10.1128/AAC.49.6.2507-2509.2005]
In vitro activity and killing effect of citropin 1.1 against gram-positive pathogens causing skin and soft tissue infections.
GIACOMETTI, Andrea;CIRIONI, OSCAR;SILVESTRI, Carmela;LICCI, ALBERTO;SCALISE, Giorgio
2005-01-01
Abstract
The in vitro activity of citropin 1.1 against gram-positive cocci was measured by MIC, minimal bactericidal concentration, time-kill studies, and a checkerboard titration method. Streptococci and staphylococci were inhibited at concentrations between 1 and 16 mg/liter, respectively. Enterococci showed less susceptibility. Synergy was demonstrated when citropin 1.1 was combined with clarithromycin and doxycycline.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
