he 4-year global drug survival of adalimumab, etanercept, and infliximab was lower than 50%, with etanercept having the best retention rate. The main positive predictor of adherence to anti-TNF-α therapy was the concomitant use of methotrexate. Our study provides further evidence that the real-life treatment of patients with RA may be different from that of randomized clinical trials.

Longterm retention of tumor necrosis factor-α inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors / Iannone, F; Gremese, E; Atzeni, F; Biasi, D; Botsios, C; Cipriani, P; Ferri, Cesarina; Foschi, V; Galeazzi, M; Gerli, R; Giardina, A; Marchesoni, A; Salaffi, F; Ziglioli, T; Lapadula, G; Grassi, W; Gruppo Italiano di Studio sulle Early Arthritides, (GISEA). - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - STAMPA. - 39:6(2012), pp. 1179-1184.

Longterm retention of tumor necrosis factor-α inhibitor therapy in a large italian cohort of patients with rheumatoid arthritis from the GISEA registry: an appraisal of predictors

FERRI, Cesarina;Salaffi F;Grassi W;
2012-01-01

Abstract

he 4-year global drug survival of adalimumab, etanercept, and infliximab was lower than 50%, with etanercept having the best retention rate. The main positive predictor of adherence to anti-TNF-α therapy was the concomitant use of methotrexate. Our study provides further evidence that the real-life treatment of patients with RA may be different from that of randomized clinical trials.
2012
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11566/73485
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