Objectives: Consumption of acid foods and drinks and other factors causing enamel wear are responsible of daily enamel loss and degradation. In order to contrast these effects, some dentifrices have been showed to possess different properties of remineralization and/or repair of the enamel surface. Methods: Two groups of patients, aged between 18 and 75 years, used for 8 weeks a dentifrice based on Zncarbonate hydroxyapatite nanocrystals (BioRepair Plus, Coswell Spa, Bologna, Italy) and a 5% potassium nitrate/sodium fluoride with 1450 ppm F dentifrice (Sensodyne ProNamel, Glaxosmith, Brentford, UK). At the end of this period, scheduled extractions were performed in 5 patients for each group. Controls consisted on 2 teeth treated with a fluoride dentifrice. All teeth were processed for a chemical-physic superficial characterization realized by SEM, Elementary EDAX probe, X-Ray Diffraction and Infrared analysis. Results: The results showed that the use of a dentifrice based on Zncarbonate hydroxyapatite nanocrystals led to a real repair of enamel erosion and loss, by means of the formation of an inorganic hydroxyapatite-like coating on the enamel surface. This newly-formed coating presented a Ca/P molar ratio of 1.67 and 1.63, which is coincident with the Ca/P molar ratio of the nanocrystals contained in the used dentifrice. No presence of silica and F were observed. On the other hand, the use of nitrate potassium/sodium fluoride dentifrice did not substantially change the enamel surface, which showed erosion signs and areas of enamel loss present also before the dentifrice treatment and similar to the control teeth, was prevalent while the Ca/P molar ratio was 1.9, which is the characteristic value of the enamel hydroxyapatite. Conclusion: This study demonstrates that Zncarbonate hydroxyapatite nanocrystals contained in the experimental dentifrice may help enamel repair by means of the formation of a reparative superficial inorganic coating.
Remineralization/repair of enamel surface by biomimeticZn-carbonate hydroxyapatite containing dentifrice / A., Lorenzini; Orsini, Giovanna; M., Lelli; M., Marchetti; I., Foltran; Sampalmieri, Francesco; Procaccini, Maurizio; N., Roveri; Putignano, Angelo. - (2011).
Remineralization/repair of enamel surface by biomimeticZn-carbonate hydroxyapatite containing dentifrice
ORSINI, Giovanna;SAMPALMIERI, FRANCESCO;PROCACCINI, Maurizio;PUTIGNANO, Angelo
2011-01-01
Abstract
Objectives: Consumption of acid foods and drinks and other factors causing enamel wear are responsible of daily enamel loss and degradation. In order to contrast these effects, some dentifrices have been showed to possess different properties of remineralization and/or repair of the enamel surface. Methods: Two groups of patients, aged between 18 and 75 years, used for 8 weeks a dentifrice based on Zncarbonate hydroxyapatite nanocrystals (BioRepair Plus, Coswell Spa, Bologna, Italy) and a 5% potassium nitrate/sodium fluoride with 1450 ppm F dentifrice (Sensodyne ProNamel, Glaxosmith, Brentford, UK). At the end of this period, scheduled extractions were performed in 5 patients for each group. Controls consisted on 2 teeth treated with a fluoride dentifrice. All teeth were processed for a chemical-physic superficial characterization realized by SEM, Elementary EDAX probe, X-Ray Diffraction and Infrared analysis. Results: The results showed that the use of a dentifrice based on Zncarbonate hydroxyapatite nanocrystals led to a real repair of enamel erosion and loss, by means of the formation of an inorganic hydroxyapatite-like coating on the enamel surface. This newly-formed coating presented a Ca/P molar ratio of 1.67 and 1.63, which is coincident with the Ca/P molar ratio of the nanocrystals contained in the used dentifrice. No presence of silica and F were observed. On the other hand, the use of nitrate potassium/sodium fluoride dentifrice did not substantially change the enamel surface, which showed erosion signs and areas of enamel loss present also before the dentifrice treatment and similar to the control teeth, was prevalent while the Ca/P molar ratio was 1.9, which is the characteristic value of the enamel hydroxyapatite. Conclusion: This study demonstrates that Zncarbonate hydroxyapatite nanocrystals contained in the experimental dentifrice may help enamel repair by means of the formation of a reparative superficial inorganic coating.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
