The possible dependence of T-wave alternans (TWA) on T-wave amplitude was investigated in 3 orthogonal leads (X, Y, Z) 20-min resting ECG recordings and in the derived vector magnitude (VM) from 176 healthy (H) subjects and 200 coronary-artery-disease (CAD) patients. After application of our adaptive-match-filter based method for parameterization of TWA in terms of its amplitude (TWA_A) and product-magnitude (TWA_PM, defined as the product of TWA A times TWA duration), and once a TW_A parameter was defined for T-wave amplitude quantification, the existence of intra- and intersubjects relationships of TWA_A and TWA_PM vs. TW_A was tested. Compared to the H-population, the CAD-population showed a significant (P < 0.05) increase of TWA_A (62±38 V vs. 54±25 microV) and TWA_PM (4029±2974 beat microV vs. 3107±1976 beat microV) and a significant decrease of TW_A (298±194 microV vs. 467±246 microV). These repolarization changes, however, occurred with no significant intra- or intersubjects relationships of TWA_A and TWA_PM vs. TW_A. Thus, in our CAD and H populations there was no evidence of TWA dependence on T-wave amplitude.

Is T-wave alternans T-wave amplitude dependent? / Burattini, Laura; Zareba, W; Burattini, Roberto. - In: BIOMEDICAL SIGNAL PROCESSING AND CONTROL. - ISSN 1746-8094. - STAMPA. - 7:(2012), pp. 358-364. [10.1016/j.bspc.2011.06.009]

Is T-wave alternans T-wave amplitude dependent?

BURATTINI, LAURA;BURATTINI, ROBERTO
2012-01-01

Abstract

The possible dependence of T-wave alternans (TWA) on T-wave amplitude was investigated in 3 orthogonal leads (X, Y, Z) 20-min resting ECG recordings and in the derived vector magnitude (VM) from 176 healthy (H) subjects and 200 coronary-artery-disease (CAD) patients. After application of our adaptive-match-filter based method for parameterization of TWA in terms of its amplitude (TWA_A) and product-magnitude (TWA_PM, defined as the product of TWA A times TWA duration), and once a TW_A parameter was defined for T-wave amplitude quantification, the existence of intra- and intersubjects relationships of TWA_A and TWA_PM vs. TW_A was tested. Compared to the H-population, the CAD-population showed a significant (P < 0.05) increase of TWA_A (62±38 V vs. 54±25 microV) and TWA_PM (4029±2974 beat microV vs. 3107±1976 beat microV) and a significant decrease of TW_A (298±194 microV vs. 467±246 microV). These repolarization changes, however, occurred with no significant intra- or intersubjects relationships of TWA_A and TWA_PM vs. TW_A. Thus, in our CAD and H populations there was no evidence of TWA dependence on T-wave amplitude.
2012
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11566/58263
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 12
  • ???jsp.display-item.citation.isi??? 11
social impact