Abstract This study was performed to evaluate the in vitro activity of the amphibian peptide aurein 1.2 and to investigate its interaction with six antibiotics against nosocomial gram-positive cocci. All isolates were inhibited at concentrations of 1 to 16 mg/liter. Synergy was demonstrated when aurein 1.2 was combined with clarithromycin and minocycline.
In Vitro Activity of Aurein 1.2 Alone and in Combination with Antibiotics against Gram-positive Nosocomial Cocci / Giacometti, Andrea; Cirioni, Oscar; Riva, A; Kamysz, W; Silvestri, C; Nadolski, P; Della Vittoria, A; Łukasiak, J; Scalise, Giorgio. - In: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. - ISSN 0066-4804. - STAMPA. - 51:4(2007), pp. 1494-1496. [10.1128/AAC.00666-06]
In Vitro Activity of Aurein 1.2 Alone and in Combination with Antibiotics against Gram-positive Nosocomial Cocci
GIACOMETTI, Andrea;CIRIONI, OSCAR;SCALISE, Giorgio
2007-01-01
Abstract
Abstract This study was performed to evaluate the in vitro activity of the amphibian peptide aurein 1.2 and to investigate its interaction with six antibiotics against nosocomial gram-positive cocci. All isolates were inhibited at concentrations of 1 to 16 mg/liter. Synergy was demonstrated when aurein 1.2 was combined with clarithromycin and minocycline.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
