Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS-Flow Cytometry Working Group

Van De Loosdrecht, A. A.; Kern, W.; Porwit, A.; Valent, P.; Kordasti, S.; Cremers, E.; Alhan, C.; Duetz, C.; Dunlop, A.; Hobo, W.; Preijers, F.; Wagner-Ballon, O.; Chapuis, N.; Fontenay, M.; Bettelheim, P.; Eidenschink-Brodersen, L.; Font, P.; Johansson, U.; Loken, M. R.; Te Marvelde, J. G.; Matarraz, S.; Ogata, K.; Oelschlaegel, U.; Orfao, A.; Psarra, K.; Subira, D.; Wells, D. A.; Bene, M. C.; Della Porta, M. G.; Burbury, K.; Bellos, F.; Van Der Velden, V. H. J.; Westers, T. M.; Saft, L.; Ireland, R.

doi:10.1002/cyto.b.22044

This article discusses the rationale for inclusion of flow cytometry (FCM) in the diagnostic investigation and evaluation of cytopenias of uncertain origin and suspected myelodysplastic syndromes (MDS) by the European LeukemiaNet international MDS Flow Working Group (ELN iMDS Flow WG). The WHO 2016 classification recognizes that FCM contributes to the diagnosis of MDS and may be useful for prognostication, prediction, and evaluation of response to therapy and follow-up of MDS patients.

Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet International MDS-Flow Cytometry Working Group / Van De Loosdrecht, A.A., Kern, W., Porwit, A., Valent, P., Kordasti, S., Cremers, E., Alhan, C., Duetz, C., Dunlop, A., Hobo, W., Preijers, F., Wagner-Ballon, O., Chapuis, N., Fontenay, M., Bettelheim, P., Eidenschink-Brodersen, L., Font, P., Johansson, U., Loken, M.R., Te Marvelde, J.G., et al.. - In: CYTOMETRY. PART B, CLINICAL CYTOMETRY. - ISSN 1552-4957. - 104:1(2023), pp. 77-86. [10.1002/cyto.b.22044]