Rhoifolin, a bioactive flavonoid with demonstrated anti-inflammatory and neuroprotective properties, represents an untapped opportunity for developing functional strawberries. We report extreme transgressive segregation (93-fold) for rhoifolin content amongst F1 progeny from cultivated strawberry ( F. × ananassa ) × Fragaria virginiana glauca crosses. LC–MS analysis revealed rhoifolin ranging from 2.1 to 195.1 million units, with genotype AN13,15,57 accumulating exceptional levels. Strong correlation between rhoifolin and rutin (ρ = 0.714, p = 0.058) validates the biological nature of this variation. Network analysis revealed coordinated elevation of 16 metabolites in high-rhoifolin genotypes, indicating systemic metabolic reprogramming rather than isolated changes. Distribution analysis suggests strong genetic control. This discovery opens immediate opportunities for marker-assisted selection of high-rhoifolin strawberries and demonstrates how wild germplasm unlocks hidden variation in cultivated fruit crops.
Extreme transgressive segregation for rhoifolin reveals breeding potential in strawberry F1 hybrids / Vallarino, J.G., Mazzoni, L., Qaderi, R., Capocasa, F., Osorio, S., Mezzetti, B.. - In: FOOD CHEMISTRY. - ISSN 1873-7072. - 518:(2026). [10.1016/j.foodchem.2026.149508]
Extreme transgressive segregation for rhoifolin reveals breeding potential in strawberry F1 hybrids
Qaderi, RohullahMembro del Collaboration Group
;Capocasa, FrancoMethodology
;Osorio, SoniaWriting – Review & Editing
;Mezzetti, Bruno
Writing – Review & Editing
2026-01-01
Abstract
Rhoifolin, a bioactive flavonoid with demonstrated anti-inflammatory and neuroprotective properties, represents an untapped opportunity for developing functional strawberries. We report extreme transgressive segregation (93-fold) for rhoifolin content amongst F1 progeny from cultivated strawberry ( F. × ananassa ) × Fragaria virginiana glauca crosses. LC–MS analysis revealed rhoifolin ranging from 2.1 to 195.1 million units, with genotype AN13,15,57 accumulating exceptional levels. Strong correlation between rhoifolin and rutin (ρ = 0.714, p = 0.058) validates the biological nature of this variation. Network analysis revealed coordinated elevation of 16 metabolites in high-rhoifolin genotypes, indicating systemic metabolic reprogramming rather than isolated changes. Distribution analysis suggests strong genetic control. This discovery opens immediate opportunities for marker-assisted selection of high-rhoifolin strawberries and demonstrates how wild germplasm unlocks hidden variation in cultivated fruit crops.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
