Enantioselective analysis is more demanding compared to non-enantioselective one from the viewpoint of time, effort and resources. At the same time if correctly designed it may bring additional information and value to forensic scientists and clinical toxicologists. This short overview describes difficulties versus the added value of enantioselective separations in forensic analysis and clinical toxicology. The specific requirements of enantioselective analytical methods as applied to forensic analysis are summarized in this review and the various separation techniques that such methods are based on are compared to each other from the perspective of forensic analysis. In the final part, the current challenges in this field are shortly reviewed and future trends are highlighted.

Enantioselective separation techniques in forensic analysis and clinical toxicology / Busardo', Francesco Paolo; Tini, Anastasio; Lo Faro, Alfredo Fabrizio; Basile, Giuseppe; Farkas, Tivadar; Chankvetadze, Bezhan. - In: TRAC. TRENDS IN ANALYTICAL CHEMISTRY. - ISSN 0165-9936. - 175:(2024). [10.1016/j.trac.2024.117733]

Enantioselective separation techniques in forensic analysis and clinical toxicology

Busardo', Francesco Paolo;Tini, Anastasio;Lo Faro, Alfredo Fabrizio;Basile, Giuseppe;
2024-01-01

Abstract

Enantioselective analysis is more demanding compared to non-enantioselective one from the viewpoint of time, effort and resources. At the same time if correctly designed it may bring additional information and value to forensic scientists and clinical toxicologists. This short overview describes difficulties versus the added value of enantioselective separations in forensic analysis and clinical toxicology. The specific requirements of enantioselective analytical methods as applied to forensic analysis are summarized in this review and the various separation techniques that such methods are based on are compared to each other from the perspective of forensic analysis. In the final part, the current challenges in this field are shortly reviewed and future trends are highlighted.
2024
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11566/344057
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