Proteins involved in zinc homeostasis may be altered in aging. This phenomenon may lead to zinc deficiency in the peripheral blood and an accumulation of zinc bound to insoluble aggregates at the extracellular level in the brain. Therefore, it should be more correct to talk about aging as a condition associated with zinc dyshomeostasis rather than deficiency. Restoring functional zinc homeostasis in aging people is an attractive field for antiaging research, but requires further knowledge than the current state of the art. © Mary Ann Liebert, Inc.
Zinc homeostasis in aging: Two elusive faces of the same "metal" / Mocchegiani, E.; Costarelli, L.; Giacconi, R.; Cipriano, C.; Muti, E.; Rink, L.; Malavolta, M.. - In: REJUVENATION RESEARCH. - ISSN 1549-1684. - 9:2(2006), pp. 351-354. [10.1089/rej.2006.9.351]
Zinc homeostasis in aging: Two elusive faces of the same "metal"
Malavolta M.Ultimo
Conceptualization
2006-01-01
Abstract
Proteins involved in zinc homeostasis may be altered in aging. This phenomenon may lead to zinc deficiency in the peripheral blood and an accumulation of zinc bound to insoluble aggregates at the extracellular level in the brain. Therefore, it should be more correct to talk about aging as a condition associated with zinc dyshomeostasis rather than deficiency. Restoring functional zinc homeostasis in aging people is an attractive field for antiaging research, but requires further knowledge than the current state of the art. © Mary Ann Liebert, Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
