Pomegranate (Punica granatum) is an important source of polyphenols with assessed antioxidant properties. The aims of this study were: (i) the characterization of the monomeric phenolic variability on each isolated fruit component (endocarp, mesocarp, aril); (ii) the study on the effect of pomegranate fruit components on human thrombin amidolytic activity. Collectively, our data show that pomegranate components contain bioactive metabolites (mainly ellagic acid) and suggest a potential role for the pomegranate extract in the regulation of a number of physio-pathological processes involving thrombin (or thrombin-like proteinase). © 2009.
Pomegranate fruit components modulate human thrombin / Cuccioloni, M.; Mozzicafreddo, M.; Sparapani, L.; Spina, M.; Eleuteri, A. M.; Fioretti, E.; Angeletti, M.. - In: FITOTERAPIA. - ISSN 1873-6971. - 80:5(2009), pp. 301-305. [10.1016/j.fitote.2009.03.009]
Pomegranate fruit components modulate human thrombin
Mozzicafreddo M.;
2009-01-01
Abstract
Pomegranate (Punica granatum) is an important source of polyphenols with assessed antioxidant properties. The aims of this study were: (i) the characterization of the monomeric phenolic variability on each isolated fruit component (endocarp, mesocarp, aril); (ii) the study on the effect of pomegranate fruit components on human thrombin amidolytic activity. Collectively, our data show that pomegranate components contain bioactive metabolites (mainly ellagic acid) and suggest a potential role for the pomegranate extract in the regulation of a number of physio-pathological processes involving thrombin (or thrombin-like proteinase). © 2009.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
