Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level. © 2013 The Royal Society of Chemistry.
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor / Margarucci, L.; Monti, M. C.; Cassiano, C.; Mozzicafreddo, M.; Angeletti, M.; Riccio, R.; Tosco, A.; Casapullo, A.. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 49:52(2013), pp. 5844-5846. [10.1039/c3cc41858h]
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor
Mozzicafreddo M.;
2013-01-01
Abstract
Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level. © 2013 The Royal Society of Chemistry.File in questo prodotto:
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