The calcium-activated chloride channel TMEM16A is involved in several physiological processes and is an important pharmacological target. Dinsdale and colleagues recently unveiled several residues in the outer pore region that constitute a critical site for the design of drugs that modulate TMEM16A channels.
Paving the way for designing drugs targeting TMEM16A / Pifferi, S.; Menini, A.. - In: TRENDS IN PHARMACOLOGICAL SCIENCES. - ISSN 0165-6147. - STAMPA. - 42:12(2021), pp. 979-980. [10.1016/j.tips.2021.10.005]
Paving the way for designing drugs targeting TMEM16A
Pifferi S.Primo
;
2021-01-01
Abstract
The calcium-activated chloride channel TMEM16A is involved in several physiological processes and is an important pharmacological target. Dinsdale and colleagues recently unveiled several residues in the outer pore region that constitute a critical site for the design of drugs that modulate TMEM16A channels.File in questo prodotto:
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