Inflamma-miRs are a group of microRNAs involved in the regulation of innate and adaptive immune responses. Increasing evidence support the contribution of dysregulated inflamma-miRs in the pathogenesis of multiple sclerosis. The aim of this study was to evaluate the expression of selected inflamma-miRs, i.e., miR-34a-5p, -125a-5p, -146a-5p, and -155, in relapsing-remitting multiple sclerosis (RRMS) and their modulation after treatment with dimethyl fumarate (DMF).
Potential prognostic value of circulating inflamma-miR-146a-5p and miR-125a-5p in relapsing-remitting multiple sclerosis / Giuliani, Angelica; Lattanzi, Simona; Ramini, Deborah; Graciotti, Laura; Danni, Maura Chiara; Procopio, Antonio Domenico; Silvestrini, Mauro; Olivieri, Fabiola; Sabbatinelli, Jacopo. - In: MULTIPLE SCLEROSIS AND RELATED DISORDERS. - ISSN 2211-0348. - 54:(2021), p. 103126. [10.1016/j.msard.2021.103126]
Potential prognostic value of circulating inflamma-miR-146a-5p and miR-125a-5p in relapsing-remitting multiple sclerosis
Giuliani, Angelica;Lattanzi, Simona;Ramini, Deborah;Graciotti, Laura;Procopio, Antonio Domenico;Silvestrini, Mauro;Olivieri, Fabiola;Sabbatinelli, Jacopo
2021-01-01
Abstract
Inflamma-miRs are a group of microRNAs involved in the regulation of innate and adaptive immune responses. Increasing evidence support the contribution of dysregulated inflamma-miRs in the pathogenesis of multiple sclerosis. The aim of this study was to evaluate the expression of selected inflamma-miRs, i.e., miR-34a-5p, -125a-5p, -146a-5p, and -155, in relapsing-remitting multiple sclerosis (RRMS) and their modulation after treatment with dimethyl fumarate (DMF).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
