Often, a student comes in excited by a revolutionary idea. When this happens, we invite the student to check the literature carefully and, moreover, to extend the search way back, for more than a century, in fact. For example, encouraged by Albert Einstein, Edward H. Synge introduced the concept of a near-field scanning microscope in the 1928 paper "A Suggested Method for Extending Microscopic Resolution Into the Ultramicroscopic Region" [1]. He claimed to have overcome the "...axiom in microscopy, that the only way to extend resolving power lies in the employment of light of smaller wavelength." For subwavelength resolution of a biological sample, Synge proposed to place an opaque screen with a 10-nm diameter pinhole within 10 nm of the sample (Figure 1). Light passing through the pinhole and the sample is focused on a photodetector. By moving the screen laterally in 10-nm steps, the sample is imaged with 10-nm resolution, regardless of the wavelength of the light. Later, what he proposed became known as a scanning near-field optical microscope (SNOM).

Scanning Microwave Microscopy for Biological Applications: Introducing the State of the Art and Inverted SMM / Farina, Marco; Hwang, James C. M.. - In: IEEE MICROWAVE MAGAZINE. - ISSN 1527-3342. - STAMPA. - 21:10(2020), pp. 52-59. [10.1109/MMM.2020.3008239]

Scanning Microwave Microscopy for Biological Applications: Introducing the State of the Art and Inverted SMM

Farina, Marco
;
2020-01-01

Abstract

Often, a student comes in excited by a revolutionary idea. When this happens, we invite the student to check the literature carefully and, moreover, to extend the search way back, for more than a century, in fact. For example, encouraged by Albert Einstein, Edward H. Synge introduced the concept of a near-field scanning microscope in the 1928 paper "A Suggested Method for Extending Microscopic Resolution Into the Ultramicroscopic Region" [1]. He claimed to have overcome the "...axiom in microscopy, that the only way to extend resolving power lies in the employment of light of smaller wavelength." For subwavelength resolution of a biological sample, Synge proposed to place an opaque screen with a 10-nm diameter pinhole within 10 nm of the sample (Figure 1). Light passing through the pinhole and the sample is focused on a photodetector. By moving the screen laterally in 10-nm steps, the sample is imaged with 10-nm resolution, regardless of the wavelength of the light. Later, what he proposed became known as a scanning near-field optical microscope (SNOM).
2020
File in questo prodotto:
File Dimensione Formato  
Scanning_Microwave_Microscopy_for_Biological_Applications_Introducing_the_State_of_the_Art_and_Inverted_SMM.pdf

Solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza d'uso: Tutti i diritti riservati
Dimensione 1.67 MB
Formato Adobe PDF
1.67 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
FinalManuscriptHwangFarina.pdf

accesso aperto

Descrizione: © 2020 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works
Tipologia: Documento in post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza d'uso: Licenza specifica dell’editore
Dimensione 837.29 kB
Formato Adobe PDF
837.29 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11566/283871
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 15
social impact