Revealing Spectrum Features of Stochastic Neuron Spike Trains

Power spectra of spike trains reveal important properties of neuronal behavior. They exhibit several peaks, whose shape and position depend on applied stimuli and intrinsic biophysical properties, such as input current density and channel noise. The position of the spectral peaks in the frequency domain is not straightforwardly predictable from statistical averages of the interspike intervals, especially when stochastic behavior prevails. In this work, we provide a model for the neuronal power spectrum, obtained from Discrete Fourier Transform and expressed as a series of expected value of sinusoidal terms. The first term of the series allows us to estimate the frequencies of the spectral peaks to a maximum error of a few Hz, and to interpret why they are not harmonics of the first peak frequency. Thus, the simple expression of the proposed power spectral density (PSD) model makes it a powerful interpretative tool of PSD shape, and also useful for neurophysiological studies aimed at extracting information on neuronal behavior from spike train spectra.