While experimental and technological attention is focused on the operational methods for hydrogen loading in metals and on the observed anomalies with respect to well-established rules, we aim to remark that these methods and these consequences can be seen as a part of a more general problem. In fact, most of the experiments and deductions of material sciences are based on the assumption that space-time is flat and isotropic (Minkowskian). After discarding this assumption, a theory of Deformed Space Time (DST) was developed in the last decades. Following this theory, experimental results were obtained which are not predicted by the Standard Model. The DST-theory concerns the fundamental interactions and in particular the nuclear ones, that can play the main role in the observed anomalies. In order to consider a nuclear reaction as a DST-reaction, four main phenomenological features were deduced: occurrence of an energy threshold; change of atomic weight; absence of gamma radiation; anisotropic emission of nuclear particles in intense beams having a very short life span. From the experimental point of view, rather than looking for fortuitous events that produce the conditions for DST-reactions, more systematic research can be undertaken by following the above reported four general rules. In particular, the occurrence of a thresholds can correspond to a latency time, necessary to reach the energy density necessary to deform space-time. The absence of gamma radiation cannot be considered as a sign that nuclear reactions are not present; in fact, in absence of detected gamma radiation elements were found which were not present before the reaction. The nuclear emissions, which are anisotropic and impulsive, can be difficult to detect with the traditional methods, thus inducing incertitude on the occurring reactions. Finally, a rapid variation of energy density is an experimental common factor of DST-reactions. Thus, the DST-theory can be the leading theory in the design of the experiment and in the interpretation of its experimental results.
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