Goal directed therapy (GDT) is able to improve mortality and reduce complications in selected high-risk patients undergoing major surgery. The aim of this study is to compare two different strategies of perioperative hemodynamic optimization: one based on optimization of preload using dynamic parameters of fluid-responsiveness and the other one based on estimated oxygen extraction rate (O2ER) as target of hemodynamic manipulation.
Estimated oxygen extraction versus dynamic parameters of fluid-responsiveness for perioperative hemodynamic optimization of patients undergoing non-cardiac surgery: a non-inferiority randomized controlled trial / Carsetti, Andrea; Amici, Mirco; Bernacconi, Tonino; Brancaleoni, Paolo; Cerutti, Elisabetta; Chiarello, Marco; Cingolani, Diego; Cola, Luisanna; Corsi, Daniela; Forlini, Giorgio; Giampieri, Marina; Iuorio, Salvatore; Principi, Tiziana; Tappatà, Giuseppe; Tempesta, Michele; Adrario, Erica; Donati, Abele. - In: BMC ANESTHESIOLOGY. - ISSN 1471-2253. - ELETTRONICO. - 20:1(2020), p. 87. [10.1186/s12871-020-01011-z]
Estimated oxygen extraction versus dynamic parameters of fluid-responsiveness for perioperative hemodynamic optimization of patients undergoing non-cardiac surgery: a non-inferiority randomized controlled trial
Carsetti, Andrea;Principi, Tiziana;Adrario, Erica;Donati, Abele
2020-01-01
Abstract
Goal directed therapy (GDT) is able to improve mortality and reduce complications in selected high-risk patients undergoing major surgery. The aim of this study is to compare two different strategies of perioperative hemodynamic optimization: one based on optimization of preload using dynamic parameters of fluid-responsiveness and the other one based on estimated oxygen extraction rate (O2ER) as target of hemodynamic manipulation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
