We have performed a detailed analysis of the conformational and segmental dynamics in lipid-based vesicles using quasielastic neutron scattering. Our data evidence the presence of dynamical heterogeneities: the hydrogens in the headgroups and in the initial part of the hydrophobic chains perform slow diffusive motions in a confined volume; those belonging to the end part of the chains show a faster confined diffusivity together with torsional isomerization transitions. A model with three hydrogen populations has been proposed to describe the main features of this complex dynamics. The addition of a charged polysaccharide component to the vesicles mostly slows the dynamics of the headgroups and of the upper part of the acyl chains without significantly affecting the isomerization dynamics.
Conformational and segmental dynamics in lipid-based vesicles / Gerelli, Yuri; Sakai, Victoria Garcìa; Ollivier, Jacques; Deriu, Antonio. - In: SOFT MATTER. - ISSN 1744-683X. - ELETTRONICO. - 7:8(2011). [10.1039/c0sm01301c]
Conformational and segmental dynamics in lipid-based vesicles
Gerelli, Yuri
Investigation
;
2011-01-01
Abstract
We have performed a detailed analysis of the conformational and segmental dynamics in lipid-based vesicles using quasielastic neutron scattering. Our data evidence the presence of dynamical heterogeneities: the hydrogens in the headgroups and in the initial part of the hydrophobic chains perform slow diffusive motions in a confined volume; those belonging to the end part of the chains show a faster confined diffusivity together with torsional isomerization transitions. A model with three hydrogen populations has been proposed to describe the main features of this complex dynamics. The addition of a charged polysaccharide component to the vesicles mostly slows the dynamics of the headgroups and of the upper part of the acyl chains without significantly affecting the isomerization dynamics.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
