Thermogenic adipocytes (i.e. brown or brite/beige adipocytes) are able to burn large amounts of lipids and carbohydrates as a result of highly active mitochondria and enhanced uncoupled respiration, due to UCP1 activity. Although mitochondria are the key organelles for this thermogenic function, limited human data are available.
Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes / Pisani, Didier F; Barquissau, Valentin; Chambard, Jean-Claude; Beuzelin, Diane; Ghandour, Rayane A; Giroud, Maude; Mairal, Aline; Pagnotta, Sophie; Cinti, Saverio; Langin, Dominique; Amri, Ez-Zoubir. - In: MOLECULAR METABOLISM. - ISSN 2212-8778. - ELETTRONICO. - 7:(2018), pp. 35-44-44. [10.1016/j.molmet.2017.11.007]
Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes
Cinti, SaverioMembro del Collaboration Group
;
2018-01-01
Abstract
Thermogenic adipocytes (i.e. brown or brite/beige adipocytes) are able to burn large amounts of lipids and carbohydrates as a result of highly active mitochondria and enhanced uncoupled respiration, due to UCP1 activity. Although mitochondria are the key organelles for this thermogenic function, limited human data are available.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
