A major group of plant antimicrobial compounds is represented by essential oils (EOs), complex mixtures of volatile secondary metabolites belonging to different chemical families. Cannabis sativa L. has been grown for thousands of years for a multiplicity of purposes; in recent years, some genotypes containing low cannabinoid concentrations have been selected and used for research purposes. Listeria monocytogenes is a facultative intracellular food pathogen, mobile for the presence of several flagella. In humans, the treatment of listeriosis is hampered by the intracellular location of listeriae and the poor intracellular penetration of some antibiotics. Flagellum-based motility has been implicated in virulence since it is critical for initial surface attachment. The purpose of this study was to investigate the antibacterial and antivirulence properties of an EO extracted from a legal C. sativa L. variety against a clinical isolate of L. monocytogenes.
FLAGELLAR MOTILITY REDUCTION IN LISTERIA MONOCYTOGENES AFTER TREATMENT WITH CANNABIS SATIVA L. ESSENTIAL OIL / Marini, Emanuela; Magi, Gloria; Giuliani, Angelica; De Dominicis, Virgina; Pavani, Marianna; Rippo, Maria Rita; Pugnaloni, Armanda; Facinelli, Bruna. - STAMPA. - 1:(2018), pp. 101-101. (Intervento presentato al convegno Pathology and Laboratory Medicine 4.0 tenutosi a Catania Centro Congressi Hotel Baia Verde nel 23-25 Ottobre 2018).