Potential Anti-Tumor Activity of Intravenous and Subcutaneous Immunoglobulin

This case study and brief review shows that IVIg can have an inhibitory role on growth and tumor spread in both solid neoplasms and lymphoproliferative diseases. Various molecular and cellular pathways are involved in this fight against tumor growth and spread, although the specific manifestations are not completely understood. There are no available data on SCIg and cancer. It is thus possible that the administration of IVIg supplemented with SCIg can help in the treatment of cancer itself and its metastases. More experimental and clinical data are necessary to confirm these preliminary observations.