Il progetto MuSICARe: la multidisciplinarietà nel contrasto dell’antimicrobico-resistenza

Antimicrobial resistance is today one of the most important public health issues in both human and veterinary medicine and is bound to become one of the major health challenges of the coming decades. The growing incidence of infections caused by multi-resistant microorganisms (MDROs) causes an increase in morbidity, mortality and costs associated with healthcare. In our country the problem of antimicrobial resistance (AMR) is made very complex by the convergence of several factors, in particular the high consumption of antibiotics in human and veterinary medicine and low adhesion to the hands hygiene. These factors have lead to a spread, among the higher in Europe, of many critical microorganisms such as carbapenemase-producing Enterobacteriaceae (CPE), methicillin-resistant Staphylococcus aureus (MRSA) or multiresistant (MDR) or pan-resistant (XDR) Acinetobacter baumannii and Pseudomonas aeruginosa. To manage this critical situation, the Ministry of Health published a National Program to Fight Antimicrobial Resistance (Piano Nazionale di Contrasto dell’Antimicrobico-Resistenza - PNCAR), which addresses the issue according to the One Health Strategy, focusing both on human and veterinary medicine. This multi-society and multi-association project aims to address the antibiotic resistance problem by implementing strategies in line with PNCAR and the WHO Global Microbial Resistance Action Plan.