The use of biologic agents in systemic immune-mediated diseases has dramatically increased in recent years, replacing conventional immunosuppressive strategies that are characterized by unspecific mechanisms of action and burdened with serious adverse effects. Biologic drugs have selective action towards specific targets, with considerable steroid-sparing effect. They are used nowadays to induce remission or treat specific organ involvements in systemic autoimmune diseases.
Biologics in inflammatory immune-mediated systemic diseases / Moroncini, Gianluca; Calogerà, Giovanni; Benfaremo, Devis; Gabrielli, Armando. - In: CURRENT PHARMACEUTICAL BIOTECHNOLOGY. - ISSN 1389-2010. - 19:(2017). [10.2174/1389201019666171226152448]
Biologics in inflammatory immune-mediated systemic diseases
Moroncini, Gianluca;CALOGERÀ, GIOVANNI;Benfaremo, Devis;Gabrielli, Armando
2017-01-01
Abstract
The use of biologic agents in systemic immune-mediated diseases has dramatically increased in recent years, replacing conventional immunosuppressive strategies that are characterized by unspecific mechanisms of action and burdened with serious adverse effects. Biologic drugs have selective action towards specific targets, with considerable steroid-sparing effect. They are used nowadays to induce remission or treat specific organ involvements in systemic autoimmune diseases.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
