mcr-1.2, an allelic variant of the transferable colistin resistance gene mcr-1, was characterized in a colistin-resistant blood isolate of Escherichia coli. It was harbored by an IncX4-type plasmid (33,293 bp). Despite its low prevalence, the potentially worrying spread of the mcr-1 gene, particularly its mcr-1.2 variant, in Italy requires increasing surveillance.
Spread of colistin resistance gene mcr-1 in Italy: characterization of the mcr-1.2 allelic variant in a colistin-resistant blood isolate of Escherichia coli / Simoni, Serena; Morroni, Gianluca; Brenciani, Andrea; Vincenzi, Chiara; Cirioni, Oscar; Castelletti, Sefora; Varaldo, Pietro E.; Giovanetti, Eleonora; Mingoia, Marina. - In: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. - ISSN 0732-8893. - 91:1(2018), pp. 66-68. [10.1016/j.diagmicrobio.2017.12.015]
Spread of colistin resistance gene mcr-1 in Italy: characterization of the mcr-1.2 allelic variant in a colistin-resistant blood isolate of Escherichia coli
Simoni, Serena;Morroni, Gianluca;Brenciani, Andrea
;Vincenzi, Chiara;Cirioni, Oscar;Castelletti, Sefora;Varaldo, Pietro E.;Giovanetti, Eleonora;Mingoia, Marina
2018-01-01
Abstract
mcr-1.2, an allelic variant of the transferable colistin resistance gene mcr-1, was characterized in a colistin-resistant blood isolate of Escherichia coli. It was harbored by an IncX4-type plasmid (33,293 bp). Despite its low prevalence, the potentially worrying spread of the mcr-1 gene, particularly its mcr-1.2 variant, in Italy requires increasing surveillance.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
