Uterine leiomyoma (also known as fibroid or myoma) is the most common benign tumor of the uterus found in women of reproductive age. It is not usually fatal but can produce serious clinical symptoms, including excessive uterine bleeding, pelvic pain or pressure, infertility and pregnancy complications. Due to lack of effective medical treatments surgery has been a definitive choice for the management of this tumor.
Extracellular matrix in uterine leiomyoma pathogenesis: a potential target for future therapeutics / Islam, Md Soriful; Ciavattini, Andrea; Petraglia, Felice; Castellucci, Mario; Ciarmela, Pasquapina. - In: HUMAN REPRODUCTION UPDATE. - ISSN 1355-4786. - 24:1(2018), pp. 59-85. [10.1093/humupd/dmx032]