445 (70%; 334 females, 110 males, 1 transsexual) out of the 636 ASSD we collected had arthritis, in the majority of cases (367, 83%) from disease onset (Group 1). Patients belonging to Group 1 with respect to Group 2 had an arthritis more commonly polyarticular and symmetrical (p=0.015), IgM-Rheumatoid factor positive (p=0.035), erosions at hands and feet plain x-rays (p=0.036) and more commonly satisfying the 1987 revised classification criteria for rheumatoid arthritis (RA) (p=0.004). Features such as Raynaud's phenomenon, mechanic's hands and fever (e.g. accompanying findings) were more frequently reported in Group 2 (p=0.005). In ASSD, the timing of appearance with respect to disease onset influences arthritis characteristics. In particular, RA features are more common when arthritis occurs from ASSD onset, suggesting an overlap between RA and ASSD in these patients. When arthritis appears during the follow-up, it is very close to a connective tissue disease-related arthritis. Also, the different prevalence of accompanying features between these two groups is in line with this possibility.
Timing of onset affects arthritis presentation pattern in antisyntethase syndrome / González Gay, Ma; Montecucco, C; Selva O'Callaghan, A; Trallero Araguas, E; Molberg, O; Andersson, H; Rojas Serrano, J; Perez Roman, Di; Bauhammer, J; Fiehn, C; Neri, R; Barsotti, S; Lorenz, Hm; Doria, Andrea; Ghirardello, A; Iannone, F; Giannini, Mattia; Franceschini, Federica; Cavazzana, I; Triantafyllias, K; Benucci, Maurizio; Infantino, M; Manfredi, LUCIANO ANTONIO; Conti, F; Schwarting, A; Sebastiani, Giovanni; Iuliano, A; Emmi, G; Silvestri, E; Govoni, Marcello; Scirè, Ca; Furini, F; Lopez Longo, Fj; Martínez Barrio, J; Sebastiani, M; Manfredi, A; Bachiller Corral, J; Sifuentes Giraldo, Wa; Cimmino, Ma; Cosso, C; Belotti Masserini, A; Cagnotto, G; Codullo, V; Romano, M; Paolazzi, G; Pellerito, R; Saketkoo, La; Ortego Centeno, N; Quartuccio, L; Batticciotto, A; Bartoloni Bocci, E; Gerli, R; Specker, C; Bravi, E; Selmi, C; Parisi, Serena; Salaffi, Fausto; Meloni, Francesca; Marchioni, E; Pesci, A; Dei, Giulia; Confalonieri, M; Tomietto, P; Nuno, L; Bonella, F; Pipitone, N; Mera Valera, A; Perez Gomez, N; Gerzeli, S; Lopez Mejias, R; Matos Costa, Cj; Pereira da Silva, Ja; Cifrian, J; Alpini, C; Olivieri, I; Blázquez Cañamero, Má; Rodriguez Cambrón, Ab; Castañeda, S; Cavagna, L.. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - STAMPA. - (2017).
Timing of onset affects arthritis presentation pattern in antisyntethase syndrome
DORIA, ANDREA;GIANNINI, MATTIA;FRANCESCHINI, Federica;BENUCCI, MAURIZIO;MANFREDI, LUCIANO ANTONIO;SEBASTIANI, GIOVANNI;GOVONI, MARCELLO;PARISI, SERENA;SALAFFI, FAUSTO;MELONI, FRANCESCA;DEI, GIULIA;
2017-01-01
Abstract
445 (70%; 334 females, 110 males, 1 transsexual) out of the 636 ASSD we collected had arthritis, in the majority of cases (367, 83%) from disease onset (Group 1). Patients belonging to Group 1 with respect to Group 2 had an arthritis more commonly polyarticular and symmetrical (p=0.015), IgM-Rheumatoid factor positive (p=0.035), erosions at hands and feet plain x-rays (p=0.036) and more commonly satisfying the 1987 revised classification criteria for rheumatoid arthritis (RA) (p=0.004). Features such as Raynaud's phenomenon, mechanic's hands and fever (e.g. accompanying findings) were more frequently reported in Group 2 (p=0.005). In ASSD, the timing of appearance with respect to disease onset influences arthritis characteristics. In particular, RA features are more common when arthritis occurs from ASSD onset, suggesting an overlap between RA and ASSD in these patients. When arthritis appears during the follow-up, it is very close to a connective tissue disease-related arthritis. Also, the different prevalence of accompanying features between these two groups is in line with this possibility.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
