Flutamide (FLU) is a non-steroidal antiandrogen drug approved for the treatment of advanced prostate cancer. While this indication limits the use to male patients, FLU is widely prescribed to women, off-label, for the treatment of polycystic ovary syndrome (POCS) related hirsutism and acne. According to the literature, its assumption is associated with a higher incidence of adverse events in women than in male patients.
Flutamide-induced hepatotoxicity: ethical and scientific issues / Giorgetti, Raffaele; di Muzio, M; Giorgetti, Arianna; Girolami, Davide; Borgia, Luisa; Tagliabracci, Adriano. - In: EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES. - ISSN 2284-0729. - 21:1 Suppl(2017), p. 69-77.
Flutamide-induced hepatotoxicity: ethical and scientific issues
GIORGETTI, RAFFAELE;GIORGETTI, ARIANNA;GIROLAMI, DAVIDE;BORGIA, LUISA;TAGLIABRACCI, Adriano
2017-01-01
Abstract
Flutamide (FLU) is a non-steroidal antiandrogen drug approved for the treatment of advanced prostate cancer. While this indication limits the use to male patients, FLU is widely prescribed to women, off-label, for the treatment of polycystic ovary syndrome (POCS) related hirsutism and acne. According to the literature, its assumption is associated with a higher incidence of adverse events in women than in male patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
