Purpose: To determine the refractive status of eyes with central serous chorioretinopathy (CSC) and investigate relationships between choroidal thickness, axial length, and refractive state in these eyes. Methods: In a prospective, case-control study, 42 consecutive subjects with CSC and 34 healthy subjects were recruited. Each participant underwent a complete ophthalmic examination, with measurement of axial length, cycloplegic autorefraction, and measurement of choroidal thickness using enhanced depth imaging spectral domain optical coherence tomography. The relationships between choroidal thickness, axial length, and refractive state were analyzed using a mixedeffects model. Results: 66 eyes of 42 subjects with CSC (mean age: 54.0 ± 12.8 years) and 68 eyes of 34 controls (mean age: 52.3 ± 17.4 years) were studied. Eyes with CSC were more hyperopic (mean: +1.24 D) than control eyes (mean: +0.09 D; p < 0.01, mixed effect model). Eyes with CSC had a shorter mean axial length of 23.06 ± 1.13 mm, compared to 23.84 ± 0.89 mm in the control group (p < 0.01). The mean choroidal thickness was 437 ± 87 μm in the CSC group and 284 ± 69 μm in the control group (p < 0.0001). In eyes with CSC, axial length was strongly correlated with the refractive state (p < 0.01); shorter eyes tended to have thicker choroids, though not in a significant manner (p=0.2). The refractive state did not correlate with the degree of choroidal thickening in eyes with CSC. Conclusions: Eyes with CSC usually exhibit a significantly thicker choroid, and many eyes with the disorder have a shorter axial length with a higher incidence of hyperopia. Axial length, rather than refractive state, may influence the degree of choroidal thickness in eyes with CSC.
Scopo dello studio: Lo scopo del nostro studio è stato quello di determinare lo stato refrattivo di occhi affetti da corioretinopatia sierosa centrale ed investigare le relazioni tra spessore coroideale, lunghezza assiale, e stato refrattivo in tali occhi. Materiali e metodi: In uno studio retrospettivo, caso-controllo, 42 soggetti consecutivi affetti da CSC e 34 soggetti sani sono stati esaminati. Ogni soggetto ha effettuato un completo esame oftalmoscopico, con misurazione della lunghezza assiale, autorefrazione cicloplegica, e misurazione dello spessore coroideale utilizzando enhanced depth imaging spectral domain optical coherence tomography. Le relazioni tra spessore coroideale, lunghezza assiale, e stato refrattivo sono state analizzate utilizzando un modello ad effetti-misti. Risultati: 66 occhi di 42 soggetti con CSC (età media: 54.0 ± 12.8 years) e 68 occhi di 34 soggetti controllo (età media: 52.3 ± 17.4 anni) sono stati studiati. Occhi con CSC erano più ipermetropi (media: +1.24 D) rispetto agli occhi controllo (media: +0.09 D; p < 0.01, mixed effect model). Occhi CSC avevano una più corta lunghezza assiale con una media di 23.06 ± 1.13 mm, confrontata a 23.84 ± 0.89 mm nel gruppo controllo (p < 0.01). La media dello spessore coroideale era 437 ± 87 μm nel gruppo CSC e 284 ± 69 μm gruppo controllo (p < 0.0001). In occhi CSC, la lunghezza assiale era fortemente correlate allo stato refrattivo (p < 0.01); occhi più corti hanno la tendenza ad una più spessa coroide, sebbene no in modo statisticamente significativo (p=0.2). Lo stato refrattivo non correlava con il grado di spessore coroideale in occhi CSC. Conclusioni: Occhi CSC usualmente esibiscono una coroide significativamente più spessa, e molti occhi con tale disordine hanno una più corta lunghezza assiale con maggiore incidenza ipermetropica. La lunghezza assiale, più che lo stato refrattivo, può influenzare il grado di spessore coroideale in occhi CSC.
Stato refrattivo, lunghezza assiale e spessore coroideale nella corioretinopatia sierosa centrale / Bruè, Claudia. - (2013 Feb 18).
Stato refrattivo, lunghezza assiale e spessore coroideale nella corioretinopatia sierosa centrale
Bruè, Claudia
2013-02-18
Abstract
Purpose: To determine the refractive status of eyes with central serous chorioretinopathy (CSC) and investigate relationships between choroidal thickness, axial length, and refractive state in these eyes. Methods: In a prospective, case-control study, 42 consecutive subjects with CSC and 34 healthy subjects were recruited. Each participant underwent a complete ophthalmic examination, with measurement of axial length, cycloplegic autorefraction, and measurement of choroidal thickness using enhanced depth imaging spectral domain optical coherence tomography. The relationships between choroidal thickness, axial length, and refractive state were analyzed using a mixedeffects model. Results: 66 eyes of 42 subjects with CSC (mean age: 54.0 ± 12.8 years) and 68 eyes of 34 controls (mean age: 52.3 ± 17.4 years) were studied. Eyes with CSC were more hyperopic (mean: +1.24 D) than control eyes (mean: +0.09 D; p < 0.01, mixed effect model). Eyes with CSC had a shorter mean axial length of 23.06 ± 1.13 mm, compared to 23.84 ± 0.89 mm in the control group (p < 0.01). The mean choroidal thickness was 437 ± 87 μm in the CSC group and 284 ± 69 μm in the control group (p < 0.0001). In eyes with CSC, axial length was strongly correlated with the refractive state (p < 0.01); shorter eyes tended to have thicker choroids, though not in a significant manner (p=0.2). The refractive state did not correlate with the degree of choroidal thickening in eyes with CSC. Conclusions: Eyes with CSC usually exhibit a significantly thicker choroid, and many eyes with the disorder have a shorter axial length with a higher incidence of hyperopia. Axial length, rather than refractive state, may influence the degree of choroidal thickness in eyes with CSC.File | Dimensione | Formato | |
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