To investigate the presence of Raf kinase inhibitor protein (RKIP) in human myometrium and leiomyoma as well as to determine the effect of locostatin (RKIP inhibitor) on extracellular matrix (ECM) production, proliferation, and migration in human myometrial and leiomyoma cells.
Locostatin, a disrupter of Raf kinase inhibitor protein, inhibits extracellular matrix production, proliferation, and migration in human uterine leiomyoma and myometrial cells / Janjusevic, Milijana; Greco, Stefania; Islam, MD SORIFUL; Castellucci, CLARA FEDERICA; Ciavattini, Andrea; Toti, Paolo; Petraglia, Felice; Ciarmela, Pasquapina. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - (2016). [10.1016/j.fertnstert.2016.08.010]