Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was A. flavus (n=10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days [158-804]. None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otologic sequelae were reported, including hearing impairment (n=7) and facial palsy (n=3).
Aspergillus spp invasive external otitis: favourable outcome with a medical approach / Marchionni, E; Parize, P; Lefevre, A; Vironneau, P; Bougnoux, M. E; Poiree, S; Coignard Biehler, H; Dewolf, S. E; Amazzough, K; Barchiesi, Francesco; Jullien, V; Alanio, A; Garcia Hermoso, D; Wassef, M; Kania, R; Lortholary, O; Lanternier, F.. - In: CLINICAL MICROBIOLOGY AND INFECTION. - ISSN 1198-743X. - ELETTRONICO. - 22:5(2016), pp. 434-437. [10.1016/j.cmi.2015.12.027]
Aspergillus spp invasive external otitis: favourable outcome with a medical approach
BARCHIESI, FRANCESCOMembro del Collaboration Group
;
2016-01-01
Abstract
Aspergillus spp. invasive external otitis (IEO) is a rare infection. We performed a seven-year, single-centre retrospective study from 2007 to 2014 including all patients with proven Aspergillus spp. IEO. Twelve patients were identified. All patients had a poorly controlled diabetes mellitus and one underwent solid organ transplant. The most frequently isolated species was A. flavus (n=10) and voriconazole was the first-line therapy in all cases, with a median length of treatment of 338.5 days [158-804]. None of the patients underwent extensive surgery. The clinical outcome was excellent. However, otologic sequelae were reported, including hearing impairment (n=7) and facial palsy (n=3).I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
