Lysosomes are promising targets for cancer and enzyme replacement therapy. In this area of interest we present a novel liposomal nanocarrier containing mannose 6-phosphate-cholesteryl conjugates and show its ability to reach the lysosomes by means of confocal and fluorescence microscopy measurements
Liposomes containing mannose-6-phosphatecholesteryl conjugates for lysosome-specific delivery / Crucianelli, Emanuela; Bruni, Paolo; Frontini, Andrea; Massaccesi, Luca; Pisani, Michela; Smorlesi, Arianna; Mobbili, Giovanna. - In: RSC ADVANCES. - ISSN 2046-2069. - 4:102(2014), pp. 58204-58207. [10.1039/c4ra08681c]
Liposomes containing mannose-6-phosphatecholesteryl conjugates for lysosome-specific delivery
CRUCIANELLI, EMANUELA;BRUNI, PAOLO;FRONTINI, ANDREA;MASSACCESI, LUCA;PISANI, MICHELA;SMORLESI, Arianna;MOBBILI, Giovanna
2014-01-01
Abstract
Lysosomes are promising targets for cancer and enzyme replacement therapy. In this area of interest we present a novel liposomal nanocarrier containing mannose 6-phosphate-cholesteryl conjugates and show its ability to reach the lysosomes by means of confocal and fluorescence microscopy measurementsFile in questo prodotto:
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