Onabotulinum-Toxin-A in Urology: An Update. A Review of Recent Publications about Lower Urinary Tract Dysfunction Managed With Botulinum Toxin

Onabotulinum toxin A (BTX-A) injection is a safe and effective treatment for adults with several conditions determining lower urinary tract dysfunctions (LUTD), such as neurogenic detrusor overactivity (NDO) and idiopathic overactive bladder (OAB) with or without urge urinary incontinence (UUI), not responder to conservative treatment options, including anticholinergic drugs. This review article analyzes recent studies who were using BTX-A to treat NDO and OAB; in addition, some other conditions causing LUTDs, such as benign prostatic hyperplasia (BPH) and painful bladder syndrome/interstitial cystitis (PBS/IC) were considered, even though in these conditions larger scale trials are still mandatory to confirm its usefulness.