Sfoglia per Autore
Effect of the COVID-19 pandemic on laboratory and clinical research: A testimony and a call to action from researchers
2020-01-01 Kabanova, A.; Gavriilaki, E.; Pelzer, B. W.; Brunetti, L.; Maiques-Diaz, A.
Large-scale GMP-compliant CRISPR-Cas9-mediated deletion of the glucocorticoid receptor in multivirus-specific T cells
2020-01-01 Basar, R.; Daher, M.; Uprety, N.; Gokdemir, E.; Alsuliman, A.; Ensley, E.; Ozcan, G.; Mendt, M.; Sanabria, M. H.; Kerbauy, L. N.; Cortes, A. K. N.; Li, L.; Banerjee, P. P.; Muniz-Feliciano, L.; Acharya, S.; Fowlkes, N. W.; Lu, J.; Li, S.; Mielke, S.; Kaplan, M.; Nandivada, V.; Bdaiwi, M.; Kontoyiannis, A. D.; Li, Y.; Liu, E.; Ang, S.; Marin, D.; Brunetti, L.; Gundry, M. C.; Turk, R.; Schubert, M. S.; Rettig, G. R.; Mcneill, M. S.; Kurgan, G.; Behlke, M. A.; Champlin, R.; Shpall, E. J.; Rezvani, K.
PU.1 subcellular localization in acute myeloid leukaemia with mutated NPM1
2020-01-01 Pianigiani, G.; Betti, C.; Bigerna, B.; Rossi, R.; Brunetti, L.
Prolonged XPO1 inhibition is essential for optimal anti-leukemic activity in NPM1-mutated AML
2021-01-01 Pianigiani, Giulia; Gagliardi, Andrea; Mezzasoma, Federica; Rocchio, Francesca; Tini, Valentina; Bigerna, Barbara; Sportoletti, Paolo; Caruso, Simona; Marra, Andrea; Spinozzi, Giulio; Shacham, Sharon; Landesman, Yosef; Quintarelli, Concetta; Locatelli, Franco; Martelli, Maria Paola; Falini, Brunangelo; Brunetti, Lorenzo
Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor
2021-01-01 Huang, Yung-Hsin; Chen, Chun-Wei; Sundaramurthy, Venkatasubramaniam; Slabicki, Mikolaj; Hao, Dapeng; Watson, Caroline J; Tovy, Ayala; Reyes, Jaime M; Dakhova, Olga; Crovetti, Brielle R; Galonska, Christina; Lee, Minjung; Brunetti, Lorenzo; Zhou, Yubin; Tatton-Brown, Katrina; Huang, Yun; Cheng, Xiaodong; Meissner, Alexander; Valk, Peter J M; Van Maldergem, Lionel; Sanders, Mathijs A; Blundell, Jamie R; Li, Wei; Ebert, Benjamin L; Goodell, Margaret A
Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML
2021-01-01 Gionfriddo, I.; Brunetti, L.; Mezzasoma, F.; Milano, F.; Cardinali, V.; Ranieri, R.; Venanzi, A.; Pierangeli, S.; Vetro, C.; Spinozzi, G.; Dorillo, E.; Wu, H. C.; Berthier, C.; Ciurnelli, R.; Griffin, M. J.; Jennings, C. E.; Tiacci, E.; Sportoletti, P.; Falzetti, F.; de The, H.; Veal, G. J.; Martelli, M. P.; Falini, B.
Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities
2021-01-01 Rogers, J. H.; Gupta, R.; Reyes, J. M.; Gundry, M. C.; Medrano, G.; Guzman, A.; Aguilar, R.; Conneely, S. E.; Song, T.; Johnson, C.; Barnes, S.; Cristobal, C. D. D.; Kurtz, K.; Brunetti, L.; Goodell, M. A.; Rau, R. E.
Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice
2021-01-01 Sportoletti, P.; Sorcini, D.; Guzman, A. G.; Reyes, J. M.; Stella, A.; Marra, A.; Sartori, S.; Brunetti, L.; Rossi, R.; Papa, B. D.; Adamo, F. M.; Pianigiani, G.; Betti, C.; Scialdone, A.; Guarente, V.; Spinozzi, G.; Tini, V.; Martelli, M. P.; Goodell, M. A.; Falini, B.
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome
2021-01-01 Tovy, Ayala; Rosas, Carina; Gaikwad, Amos S; Medrano, Geraldo; Zhang, Linda; Reyes, Jaime M; Huang, Yung-Hsin; Arakawa, Tastuhiko; Kurtz, Kristen; Conneely, Shannon E; Guzman, Anna G; Aguilar, Rogelio; Gao, Anne; Chen, Chun-Wei; Kim, Jean J; Carter, Melissa T; Lasa-Aranzasti, Amaia; Valenzuela, Irene; Van Maldergem, Lionel; Brunetti, Lorenzo; Hicks, M John; Marcogliese, Andrea N; Goodell, Margaret A; Rau, Rachel E
Diagnostic and therapeutic pitfalls in NPM1-mutated AML: notes from the field
2021-01-01 Falini, B.; Sciabolacci, S.; Falini, L.; Brunetti, L.; Martelli, M. P.
Actinomycin d targets npm1c-primed mitochondria to restore pml-driven senescence in aml therapy
2021-01-01 Wu, H. -C.; Rerolle, D.; Berthier, C.; Hleihel, R.; Sakamoto, T.; Quentin, S.; Benhenda, S.; Morganti, C.; Wu, C.; Conte, L.; Rimsky, S.; Sebert, M.; Clappier, E.; Souquere, S.; Gachet, S.; Soulier, J.; Durand, S.; Trowbridge, J. J.; Benit, P.; Rustin, P.; Hajj, H. E.; Raffoux, E.; Ades, L.; Itzykson, R.; Dombret, H.; Fenaux, P.; Espeli, O.; Kroemer, G.; Brunetti, L.; Mak, T. W.; Lallemand-Breitenbach, V.; Bazarbachi, A.; Falini, B.; Ito, K.; Martelli, M. P.; de The, H.
NOVEL NPM1 EXON 5 MUTATIONS AND GENE FUSIONS LEADING TO ABERRANT CYTOPLASMIC NUCLEOPHOSMIN IN AML
2021-01-01 Martelli, Maria Paola; Rossi, Roberta; Venanzi, Alessandra; Meggendorfer, Manja; Perriello, Vincenzo Maria; Martino, Giovanni; Spinelli, Orietta; Ciurnelli, Raffaella; Varasano, Emanuela; Brunetti, Lorenzo; Ascani, Stefano; Quadalti, Corinne; Cardinali, Valeria; Mezzasoma, Federica; Gionfriddo, Ilaria; Milano, Francesca; Pacini, Roberta; Tabarrini, Alessia; Bigerna, Barbara; Albano, Francesco; Specchia, Giorgina; Vetro, Calogero; Di Raimondo, Francesco; Annibali, Ombretta; Avvisati, Giuseppe; Rambaldi, Alessandro; Falzetti, Franca; Tiacci, Enrico; Sportoletti, Paolo; Haferlach, Torsten; Haferlach, Claudia; Falini, Brunangelo
CD123 is consistently expressed on NPM1-mutated AML cells
2021-01-01 Perriello, V. M.; Gionfriddo, I.; Rossi, R.; Milano, F.; Mezzasoma, F.; Marra, A.; Spinelli, O.; Rambaldi, A.; Annibali, O.; Avvisati, G.; Di Raimondo, F.; Ascani, S.; Falini, B.; Martelli, M. P.; Brunetti, L.
CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression
2021-01-01 Fousek, K.; Watanabe, J.; Joseph, S. K.; George, A.; An, X.; Byrd, T. T.; Morris, J. S.; Luong, A.; Martinez-Paniagua, M. A.; Sanber, K.; Navai, S. A.; Gad, A. Z.; Salsman, V. S.; Mathew, P. R.; Kim, H. N.; Wagner, D. L.; Brunetti, L.; Jang, A.; Baker, M. L.; Varadarajan, N.; Hegde, M.; Kim, Y. -M.; Heisterkamp, N.; Abdel-Azim, H.; Ahmed, N.
How I diagnose and treat NPM1-mutated AML
2021-01-01 Falini, B.; Brunetti, L.; Martelli, M. P.
Prenatal diagnosis of familial hemophagocytic lymphohistiocytosis: morphological findings in the product of conception
2021-01-01 Zanelli, M.; Zizzo, M.; Sanguedolce, F.; Martino, G.; Brunetti, L.; Ascani, S.
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells
2021-01-01 Daher, M.; Basar, R.; Gokdemir, E.; Baran, N.; Uprety, N.; Nunez Cortes, A. K.; Mendt, M.; Kerbauy, L. N.; Banerjee, P. P.; Shanley, M.; Imahashi, N.; Li, L.; Lim, F. L. W. I.; Fathi, M.; Rezvan, A.; Mohanty, V.; Shen, Y.; Shaim, H.; Lu, J.; Ozcan, G.; Ensley, E.; Kaplan, M.; Nandivada, V.; Bdiwi, M.; Acharya, S.; Xi, Y.; Wan, X.; Mak, D.; Liu, E.; Jiang, X. R.; Ang, S.; Muniz-Feliciano, L.; Li, Y.; Wang, J.; Kordasti, S.; Petrov, N.; Varadarajan, N.; Marin, D.; Brunetti, L.; Skinner, R. J.; Lyu, S.; Silva, L.; Turk, R.; Schubert, M. S.; Rettig, G. R.; Mcneill, M. S.; Kurgan, G.; Behlke, M. A.; Li, H.; Fowlkes, N. W.; Chen, K.; Konopleva, M.; Champlin, R. E.; Shpall, E. J.; Rezvani, K.
Overlapping features of therapy-related and de novoNPM1-mutated AML
2022-01-01 Othman, Jad; Meggendorfer, Manja; Tiacci, Enrico; Thiede, Christian; Schlenk, Richard F; Dillon, Richard; Stasik, Sebastian; Venanzi, Alessandra; Bertoli, Sarah; Delabesse, Eric; Dumas, Pierre-Yves; Pigneux, Arnaud; Bidet, Audrey; Gilkes, Amanda Frances; Thomas, Ian; Voso, Maria Teresa; Rambaldi, Alessandro; Brunetti, Lorenzo; Perriello, Vincenzo Maria; Andresen, Vibeke; Gjertsen, Bjorn T; Martelli, Maria Paola; Récher, Christian; Röllig, Christoph; Bornhäuser, Martin; Serve, Hubert; Müller-Tidow, Carsten; Baldus, Claudia D; Haferlach, Torsten; Russell, Nigel H; Falini, Brunangelo
The absent/low expression of CD34 in NPM1-mutated AML is not related to cytoplasmic dislocation of NPM1 mutant protein
2022-01-01 Pianigiani, Giulia; Rocchio, Francesca; Peruzzi, Sara; Andresen, Vibeke; Bigerna, Barbara; Sorcini, Daniele; Capurro, Michela; Gjertsen, Bjørn Tore; Sportoletti, Paolo; Di Ianni, Mauro; Martelli, Maria Paola; Brunetti, Lorenzo; Falini, Brunangelo
Current status and future perspectives in targeted therapy of NPM1-mutated AML
2022-01-01 Ranieri, R.; Pianigiani, G.; Sciabolacci, S.; Perriello, V. M.; Marra, A.; Cardinali, V.; Pierangeli, S.; Milano, F.; Gionfriddo, I.; Brunetti, L.; Martelli, M. P.; Falini, B.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Effect of the COVID-19 pandemic on laboratory and clinical research: A testimony and a call to action from researchers | 1-gen-2020 | Kabanova, A.; Gavriilaki, E.; Pelzer, B. W.; Brunetti, L.; Maiques-Diaz, A. | |
| Large-scale GMP-compliant CRISPR-Cas9-mediated deletion of the glucocorticoid receptor in multivirus-specific T cells | 1-gen-2020 | Basar, R.; Daher, M.; Uprety, N.; Gokdemir, E.; Alsuliman, A.; Ensley, E.; Ozcan, G.; Mendt, M.; Sanabria, M. H.; Kerbauy, L. N.; Cortes, A. K. N.; Li, L.; Banerjee, P. P.; Muniz-Feliciano, L.; Acharya, S.; Fowlkes, N. W.; Lu, J.; Li, S.; Mielke, S.; Kaplan, M.; Nandivada, V.; Bdaiwi, M.; Kontoyiannis, A. D.; Li, Y.; Liu, E.; Ang, S.; Marin, D.; Brunetti, L.; Gundry, M. C.; Turk, R.; Schubert, M. S.; Rettig, G. R.; Mcneill, M. S.; Kurgan, G.; Behlke, M. A.; Champlin, R.; Shpall, E. J.; Rezvani, K. | |
| PU.1 subcellular localization in acute myeloid leukaemia with mutated NPM1 | 1-gen-2020 | Pianigiani, G.; Betti, C.; Bigerna, B.; Rossi, R.; Brunetti, L. | |
| Prolonged XPO1 inhibition is essential for optimal anti-leukemic activity in NPM1-mutated AML | 1-gen-2021 | Pianigiani, Giulia; Gagliardi, Andrea; Mezzasoma, Federica; Rocchio, Francesca; Tini, Valentina; Bigerna, Barbara; Sportoletti, Paolo; Caruso, Simona; Marra, Andrea; Spinozzi, Giulio; Shacham, Sharon; Landesman, Yosef; Quintarelli, Concetta; Locatelli, Franco; Martelli, Maria Paola; Falini, Brunangelo; Brunetti, Lorenzo | |
| Systematic profiling of DNMT3A variants reveals protein instability mediated by the DCAF8 E3 ubiquitin ligase adaptor | 1-gen-2021 | Huang, Yung-Hsin; Chen, Chun-Wei; Sundaramurthy, Venkatasubramaniam; Slabicki, Mikolaj; Hao, Dapeng; Watson, Caroline J; Tovy, Ayala; Reyes, Jaime M; Dakhova, Olga; Crovetti, Brielle R; Galonska, Christina; Lee, Minjung; Brunetti, Lorenzo; Zhou, Yubin; Tatton-Brown, Katrina; Huang, Yun; Cheng, Xiaodong; Meissner, Alexander; Valk, Peter J M; Van Maldergem, Lionel; Sanders, Mathijs A; Blundell, Jamie R; Li, Wei; Ebert, Benjamin L; Goodell, Margaret A | |
| Dactinomycin induces complete remission associated with nucleolar stress response in relapsed/refractory NPM1-mutated AML | 1-gen-2021 | Gionfriddo, I.; Brunetti, L.; Mezzasoma, F.; Milano, F.; Cardinali, V.; Ranieri, R.; Venanzi, A.; Pierangeli, S.; Vetro, C.; Spinozzi, G.; Dorillo, E.; Wu, H. C.; Berthier, C.; Ciurnelli, R.; Griffin, M. J.; Jennings, C. E.; Tiacci, E.; Sportoletti, P.; Falzetti, F.; de The, H.; Veal, G. J.; Martelli, M. P.; Falini, B. | |
| Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities | 1-gen-2021 | Rogers, J. H.; Gupta, R.; Reyes, J. M.; Gundry, M. C.; Medrano, G.; Guzman, A.; Aguilar, R.; Conneely, S. E.; Song, T.; Johnson, C.; Barnes, S.; Cristobal, C. D. D.; Kurtz, K.; Brunetti, L.; Goodell, M. A.; Rau, R. E. | |
| Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice | 1-gen-2021 | Sportoletti, P.; Sorcini, D.; Guzman, A. G.; Reyes, J. M.; Stella, A.; Marra, A.; Sartori, S.; Brunetti, L.; Rossi, R.; Papa, B. D.; Adamo, F. M.; Pianigiani, G.; Betti, C.; Scialdone, A.; Guarente, V.; Spinozzi, G.; Tini, V.; Martelli, M. P.; Goodell, M. A.; Falini, B. | |
| Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome | 1-gen-2021 | Tovy, Ayala; Rosas, Carina; Gaikwad, Amos S; Medrano, Geraldo; Zhang, Linda; Reyes, Jaime M; Huang, Yung-Hsin; Arakawa, Tastuhiko; Kurtz, Kristen; Conneely, Shannon E; Guzman, Anna G; Aguilar, Rogelio; Gao, Anne; Chen, Chun-Wei; Kim, Jean J; Carter, Melissa T; Lasa-Aranzasti, Amaia; Valenzuela, Irene; Van Maldergem, Lionel; Brunetti, Lorenzo; Hicks, M John; Marcogliese, Andrea N; Goodell, Margaret A; Rau, Rachel E | |
| Diagnostic and therapeutic pitfalls in NPM1-mutated AML: notes from the field | 1-gen-2021 | Falini, B.; Sciabolacci, S.; Falini, L.; Brunetti, L.; Martelli, M. P. | |
| Actinomycin d targets npm1c-primed mitochondria to restore pml-driven senescence in aml therapy | 1-gen-2021 | Wu, H. -C.; Rerolle, D.; Berthier, C.; Hleihel, R.; Sakamoto, T.; Quentin, S.; Benhenda, S.; Morganti, C.; Wu, C.; Conte, L.; Rimsky, S.; Sebert, M.; Clappier, E.; Souquere, S.; Gachet, S.; Soulier, J.; Durand, S.; Trowbridge, J. J.; Benit, P.; Rustin, P.; Hajj, H. E.; Raffoux, E.; Ades, L.; Itzykson, R.; Dombret, H.; Fenaux, P.; Espeli, O.; Kroemer, G.; Brunetti, L.; Mak, T. W.; Lallemand-Breitenbach, V.; Bazarbachi, A.; Falini, B.; Ito, K.; Martelli, M. P.; de The, H. | |
| NOVEL NPM1 EXON 5 MUTATIONS AND GENE FUSIONS LEADING TO ABERRANT CYTOPLASMIC NUCLEOPHOSMIN IN AML | 1-gen-2021 | Martelli, Maria Paola; Rossi, Roberta; Venanzi, Alessandra; Meggendorfer, Manja; Perriello, Vincenzo Maria; Martino, Giovanni; Spinelli, Orietta; Ciurnelli, Raffaella; Varasano, Emanuela; Brunetti, Lorenzo; Ascani, Stefano; Quadalti, Corinne; Cardinali, Valeria; Mezzasoma, Federica; Gionfriddo, Ilaria; Milano, Francesca; Pacini, Roberta; Tabarrini, Alessia; Bigerna, Barbara; Albano, Francesco; Specchia, Giorgina; Vetro, Calogero; Di Raimondo, Francesco; Annibali, Ombretta; Avvisati, Giuseppe; Rambaldi, Alessandro; Falzetti, Franca; Tiacci, Enrico; Sportoletti, Paolo; Haferlach, Torsten; Haferlach, Claudia; Falini, Brunangelo | |
| CD123 is consistently expressed on NPM1-mutated AML cells | 1-gen-2021 | Perriello, V. M.; Gionfriddo, I.; Rossi, R.; Milano, F.; Mezzasoma, F.; Marra, A.; Spinelli, O.; Rambaldi, A.; Annibali, O.; Avvisati, G.; Di Raimondo, F.; Ascani, S.; Falini, B.; Martelli, M. P.; Brunetti, L. | |
| CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression | 1-gen-2021 | Fousek, K.; Watanabe, J.; Joseph, S. K.; George, A.; An, X.; Byrd, T. T.; Morris, J. S.; Luong, A.; Martinez-Paniagua, M. A.; Sanber, K.; Navai, S. A.; Gad, A. Z.; Salsman, V. S.; Mathew, P. R.; Kim, H. N.; Wagner, D. L.; Brunetti, L.; Jang, A.; Baker, M. L.; Varadarajan, N.; Hegde, M.; Kim, Y. -M.; Heisterkamp, N.; Abdel-Azim, H.; Ahmed, N. | |
| How I diagnose and treat NPM1-mutated AML | 1-gen-2021 | Falini, B.; Brunetti, L.; Martelli, M. P. | |
| Prenatal diagnosis of familial hemophagocytic lymphohistiocytosis: morphological findings in the product of conception | 1-gen-2021 | Zanelli, M.; Zizzo, M.; Sanguedolce, F.; Martino, G.; Brunetti, L.; Ascani, S. | |
| Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells | 1-gen-2021 | Daher, M.; Basar, R.; Gokdemir, E.; Baran, N.; Uprety, N.; Nunez Cortes, A. K.; Mendt, M.; Kerbauy, L. N.; Banerjee, P. P.; Shanley, M.; Imahashi, N.; Li, L.; Lim, F. L. W. I.; Fathi, M.; Rezvan, A.; Mohanty, V.; Shen, Y.; Shaim, H.; Lu, J.; Ozcan, G.; Ensley, E.; Kaplan, M.; Nandivada, V.; Bdiwi, M.; Acharya, S.; Xi, Y.; Wan, X.; Mak, D.; Liu, E.; Jiang, X. R.; Ang, S.; Muniz-Feliciano, L.; Li, Y.; Wang, J.; Kordasti, S.; Petrov, N.; Varadarajan, N.; Marin, D.; Brunetti, L.; Skinner, R. J.; Lyu, S.; Silva, L.; Turk, R.; Schubert, M. S.; Rettig, G. R.; Mcneill, M. S.; Kurgan, G.; Behlke, M. A.; Li, H.; Fowlkes, N. W.; Chen, K.; Konopleva, M.; Champlin, R. E.; Shpall, E. J.; Rezvani, K. | |
| Overlapping features of therapy-related and de novoNPM1-mutated AML | 1-gen-2022 | Othman, Jad; Meggendorfer, Manja; Tiacci, Enrico; Thiede, Christian; Schlenk, Richard F; Dillon, Richard; Stasik, Sebastian; Venanzi, Alessandra; Bertoli, Sarah; Delabesse, Eric; Dumas, Pierre-Yves; Pigneux, Arnaud; Bidet, Audrey; Gilkes, Amanda Frances; Thomas, Ian; Voso, Maria Teresa; Rambaldi, Alessandro; Brunetti, Lorenzo; Perriello, Vincenzo Maria; Andresen, Vibeke; Gjertsen, Bjorn T; Martelli, Maria Paola; Récher, Christian; Röllig, Christoph; Bornhäuser, Martin; Serve, Hubert; Müller-Tidow, Carsten; Baldus, Claudia D; Haferlach, Torsten; Russell, Nigel H; Falini, Brunangelo | |
| The absent/low expression of CD34 in NPM1-mutated AML is not related to cytoplasmic dislocation of NPM1 mutant protein | 1-gen-2022 | Pianigiani, Giulia; Rocchio, Francesca; Peruzzi, Sara; Andresen, Vibeke; Bigerna, Barbara; Sorcini, Daniele; Capurro, Michela; Gjertsen, Bjørn Tore; Sportoletti, Paolo; Di Ianni, Mauro; Martelli, Maria Paola; Brunetti, Lorenzo; Falini, Brunangelo | |
| Current status and future perspectives in targeted therapy of NPM1-mutated AML | 1-gen-2022 | Ranieri, R.; Pianigiani, G.; Sciabolacci, S.; Perriello, V. M.; Marra, A.; Cardinali, V.; Pierangeli, S.; Milano, F.; Gionfriddo, I.; Brunetti, L.; Martelli, M. P.; Falini, B. |
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