Stem cell-based tissue engineering therapies involve the administration of ex vivo manipulated stem cell populations for the purpose of repairing and regenerating damaged or diseased tissue. Currently available methods for monitoring transplanted cells are limited. Monitoring stem cell therapy outcomes requires the development of nondestructive strategies capable to identify the location, magnitude, and duration of cellular survival and fate. The recent development of imaging techniques offers great potential for addressing these critical issues by noninvasively tracking the fate of the transplanted cells. We offer a focused presentation of some examples of the use of imaging techniques connected to the nanotechnological world in research areas related to stem cells. In particular, investigations concerning human stem cell treatment of Duchenne muscular dystrophy in animal models, bioscaffolds for cell proliferation to form muscular fi bers, and bone tissue engineering are discussed.

Chapter 8: Synchroton Radiation and Nanotechnology for Stem Cell Researchers

FIORI, FABRIZIO;GIULIANI, ALESSANDRA;MANESCU, Adrian;RENGHINI, CHIARA;RUSTICHELLI, Franco
2012-01-01

Abstract

Stem cell-based tissue engineering therapies involve the administration of ex vivo manipulated stem cell populations for the purpose of repairing and regenerating damaged or diseased tissue. Currently available methods for monitoring transplanted cells are limited. Monitoring stem cell therapy outcomes requires the development of nondestructive strategies capable to identify the location, magnitude, and duration of cellular survival and fate. The recent development of imaging techniques offers great potential for addressing these critical issues by noninvasively tracking the fate of the transplanted cells. We offer a focused presentation of some examples of the use of imaging techniques connected to the nanotechnological world in research areas related to stem cells. In particular, investigations concerning human stem cell treatment of Duchenne muscular dystrophy in animal models, bioscaffolds for cell proliferation to form muscular fi bers, and bone tissue engineering are discussed.
9781617796296
9781617796302
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11566/65945
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact