Hidradenitis suppurativa (or Acne inversa or Verneuil.s disease) is an inflammatory, debilitating skin disease with multiple flare-ups. It affects the apocrine gland-bearing areas with boils, sinus tracts, fistulae and scarring. Patients afflicted by HS have severe discomfort and psychosocial costs (Esmann S et al., 2011). Despite that, HS has a significant underestimated morbidity and it still results in a high unmet medical need. This is probably due to the fragmented knowledge of the pathogenesis of HS. HS is notoriously difficult and challenging to treat. The use of botulinum toxin A has recently been proposed as an effective therapy for HS.
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