Fetal T-wave alternans (TWA) is a still littleknown marker for severe fetus-heart instabilities and may be related to some currently unjustified fetal deaths. Automatically detecting TWA on direct fetal electrocardiograms (DFECG) means possibility of providing fetuses the right treatment during delivery. Instead, automatically identifying TWA on indirect fetal electrocardiograms (IFECG) means possibility of providing fetuses the right treatment even during pregnancy, when taking actions for outcome improvement is still possible. Moreover, TWA identification from IFECG is noninvasive, and thus safe for both fetuses and mothers. The aim of this work was testing the heart-rate adaptive match filter (HRAMF) for automatic TWA identification in IFECG and comparing HRAMF performance in IFECG against DFECG. To this aim, simultaneously recorded DFECG and IFECG tracings from 5 healthy fetuses were used ('Abdominal and Direct Fetal Electrocardiogram Database' from Physionet). TWA measurements (frequency, mean amplitude, maximum amplitude, and amplitude standard deviation) in IFECG (1.09±0.04 Hz, 11±5 μV, 21±12 μV and 7±3 μV) were of the same order of magnitude of those in DFECG (1.07±0.02 Hz, 9±2 μV, 30±11 μV and 6±2 μV). Moreover, a direct correlation (ñ) was found between maximum TWA and fetal heart rate (IFECG: ρ=0.999; P=0.022; DEFEG: ρ=0.642; P=0.243). Thus, HRAMF was able to detect TWA from IFECG as well as from DFECG.
Automatic T-Wave Alternans Identification in Indirect and Direct Fetal Electrocardiography / Marcantoni, Ilaria; Sbrollini, Agnese; Burattini, Luca; Morettini, Micaela; Fioretti, Sandro; Burattini, Laura. - ELETTRONICO. - 2018-:(2018), pp. 4852-4855. (Intervento presentato al convegno 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018 tenutosi a Hawaii Convention Center, usa nel 2018) [10.1109/EMBC.2018.8513109].
Automatic T-Wave Alternans Identification in Indirect and Direct Fetal Electrocardiography
Marcantoni, Ilaria;Sbrollini, Agnese;Morettini, Micaela;Fioretti, Sandro;Burattini, Laura
2018-01-01
Abstract
Fetal T-wave alternans (TWA) is a still littleknown marker for severe fetus-heart instabilities and may be related to some currently unjustified fetal deaths. Automatically detecting TWA on direct fetal electrocardiograms (DFECG) means possibility of providing fetuses the right treatment during delivery. Instead, automatically identifying TWA on indirect fetal electrocardiograms (IFECG) means possibility of providing fetuses the right treatment even during pregnancy, when taking actions for outcome improvement is still possible. Moreover, TWA identification from IFECG is noninvasive, and thus safe for both fetuses and mothers. The aim of this work was testing the heart-rate adaptive match filter (HRAMF) for automatic TWA identification in IFECG and comparing HRAMF performance in IFECG against DFECG. To this aim, simultaneously recorded DFECG and IFECG tracings from 5 healthy fetuses were used ('Abdominal and Direct Fetal Electrocardiogram Database' from Physionet). TWA measurements (frequency, mean amplitude, maximum amplitude, and amplitude standard deviation) in IFECG (1.09±0.04 Hz, 11±5 μV, 21±12 μV and 7±3 μV) were of the same order of magnitude of those in DFECG (1.07±0.02 Hz, 9±2 μV, 30±11 μV and 6±2 μV). Moreover, a direct correlation (ñ) was found between maximum TWA and fetal heart rate (IFECG: ρ=0.999; P=0.022; DEFEG: ρ=0.642; P=0.243). Thus, HRAMF was able to detect TWA from IFECG as well as from DFECG.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
