Sfoglia per Autore
Characterization of the NAD biosynthesis in Francisella tularensis
2010-01-01 Zogaj, X.; Sorci, Leonardo; Osterman, A. L.; Klose, K. E.
Genomics-driven reconstruction of Acinetobacter NAD metabolism: insights for antibacterial target selection
2010-01-01 Sorci, Leonardo; Blaby, I; DE INGENIIS, Jessica; Gerdes, S; Raffaelli, Nadia; DE CRECY LAGARD, V; Osterman, A.
Genomics and Enzymology of NAD Biosynthesis
2010-01-01 Sorci, Leonardo; Kurnasov, O.; Rodionov, D. A.; Osterman, A. L.
Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement
2010-01-01 Huang, N.; Kolhatkar, R.; Eyobo, Y.; Sorci, Leonardo; Rodionova, I.; Osterman, A. L.; Mackerell, A. D.; Zhang, H.
NAD biosynthesis under attack
2011-01-01 Sorci, Leonardo; Rodionova, I.; Blaby, I. K.; De Ingeniis, J.; De Crécy Lagard, V.; Osterman, A. L.
Eubacterial pyridine nucleotide cycle: identification and characterization of the 'orphan enzyme' nmn deamidase
2011-01-01 Bocci, P.; Galeazzi, L.; Amici, Adolfo; Brunetti, L.; Sorci, Leonardo; Osterman, A.; Romine, M.; Reed, S.; Raffaelli, Nadia
Identification of Nicotinamide Mononucleotide Deamidase of the Bacterial Pyridine Nucleotide Cycle Reveals a Novel Broadly Conserved Amidohydrolase Family
2011-01-01 Galeazzi, Luca; Bocci, P.; Amici, Adolfo; Brunetti, Lucia; Ruggieri, Silverio; Romine, M.; Reed, S.; Osterman, A. L.; Rodionov, D. A.; Sorci, Leonardo; Raffaelli, Nadia
The enzyme NMN deamidase of the bacterial pyridine nucleotide cycle is a novel, broadly conserved amidohydrolase
2011-01-01 Raffaelli, Nadia; Bocci, P.; Galeazzi, L.; Amici, Adolfo; Brunetti, L.; Ruggieri, Silverio; Reed, S.; Romine, M.; Osterman, A. L.; Rodionov, D.; Sorci, Leonardo
Structural biology of NAD metabolism in bacteria
2011-01-01 Huang, N.; Eyobo, Y.; Sorci, Leonardo; Osterman, A. L.; Hong, Z.
NAD biosynthesis enzymes from the bacterial world as valuable tools for vitamin B3 mononucleotides quantitation in mammals
2012-01-01 Carradori, R; Mori, V; Amici, Adolfo; Orsomando, Giuseppe; Sorci, Leonardo; Mazzola, F; Bocci, Paola; Ruggieri, Silverio; Raffaelli, Nadia
Glutamine versus Ammonia Utilization in the NAD Synthetase Family.
2012-01-01 De Ingeniis, J; Kazanov, Md; Shatalin, K; Gelfand, Ms; Osterman, Al; Sorci, Leonardo
S. pyogenes is reliant on salvage of host pyridine precursors for NAD synthesis: implications for pathogenesis and antibacterial intervention
2012-01-01 Sorci, Leonardo; Blaby, Ik; De Crécy Lagard, V; Osterman, A.
Quinolinate salvage and insights for targeting NAD biosynthesis in group A Streptococci.
2013-01-01 Sorci, Leonardo; Blaby, Ik; Rodionova, Ia; De Ingeniis, J; Tkachenko, S; de Crécy Lagard, V; Osterman, Al
Genomics-Guided Analysis of NAD Recycling Yields Functional Elucidation of COG1058 as a New Family of Pyrophosphatases
2013-01-01 Cialabrini, L.; Ruggieri, Silverio; Kazanov, M. D.; Sorci, Leonardo; Mazzola, Francesca; Orsomando, Giuseppe; Osterman, A. L.; Raffaelli, Nadia
NAD homeostasis in the bacterial response to DNA/RNA damage.
2014-01-01 Sorci, Leonardo; Ruggieri, Silverio; Raffaelli, Nadia
Nicotinate phosphoribosyltransferase: a novel antiinfective target?
2014-01-01 Sorci, Leonardo; Anton, Cheltsov; Massaccesi, Luca; Galeazzi, Roberta
Metabolic and Bactericidal Effects of Targeted Suppression of NadD and NadE Enzymes in Mycobacteria
2014-01-01 Rodionova, Ia; Schuster, Bm; Guinn, Km; Sorci, Leonardo; Scott, Da; Li, X; Kheterpal, I; Shoen, C; Cynamon, M; Locher, C; Rubin, Ej; Osterman, A. L.
Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases.
2014-01-01 Sorci, Leonardo; Brunetti, L; Cialabrini, L; Mazzola, Francesca; Kazanov, Md; D'Auria, S; Ruggieri, Silverio; Raffaelli, Nadia
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues
2015-01-01 Ruggieri, Silverio; Orsomando, Giuseppe; Sorci, Leonardo; Raffaelli, Nadia
Mycobacterial Nicotinate Mononucleotide Adenylyltransferase: STRUCTURE, MECHANISM, AND IMPLICATIONS FOR DRUG DISCOVERY
2015-01-01 Rodionova, Irina A; Zuccola, Harmon J; Sorci, Leonardo; Aleshin, Alexander E; Kazanov, Marat D; Ma, Chen Ting; Sergienko, Eduard; Rubin, Eric J; Locher, Christopher P; Osterman, Andrei L.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Characterization of the NAD biosynthesis in Francisella tularensis | 1-gen-2010 | Zogaj, X.; Sorci, Leonardo; Osterman, A. L.; Klose, K. E. | |
Genomics-driven reconstruction of Acinetobacter NAD metabolism: insights for antibacterial target selection | 1-gen-2010 | Sorci, Leonardo; Blaby, I; DE INGENIIS, Jessica; Gerdes, S; Raffaelli, Nadia; DE CRECY LAGARD, V; Osterman, A. | |
Genomics and Enzymology of NAD Biosynthesis | 1-gen-2010 | Sorci, Leonardo; Kurnasov, O.; Rodionov, D. A.; Osterman, A. L. | |
Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement | 1-gen-2010 | Huang, N.; Kolhatkar, R.; Eyobo, Y.; Sorci, Leonardo; Rodionova, I.; Osterman, A. L.; Mackerell, A. D.; Zhang, H. | |
NAD biosynthesis under attack | 1-gen-2011 | Sorci, Leonardo; Rodionova, I.; Blaby, I. K.; De Ingeniis, J.; De Crécy Lagard, V.; Osterman, A. L. | |
Eubacterial pyridine nucleotide cycle: identification and characterization of the 'orphan enzyme' nmn deamidase | 1-gen-2011 | Bocci, P.; Galeazzi, L.; Amici, Adolfo; Brunetti, L.; Sorci, Leonardo; Osterman, A.; Romine, M.; Reed, S.; Raffaelli, Nadia | |
Identification of Nicotinamide Mononucleotide Deamidase of the Bacterial Pyridine Nucleotide Cycle Reveals a Novel Broadly Conserved Amidohydrolase Family | 1-gen-2011 | Galeazzi, Luca; Bocci, P.; Amici, Adolfo; Brunetti, Lucia; Ruggieri, Silverio; Romine, M.; Reed, S.; Osterman, A. L.; Rodionov, D. A.; Sorci, Leonardo; Raffaelli, Nadia | |
The enzyme NMN deamidase of the bacterial pyridine nucleotide cycle is a novel, broadly conserved amidohydrolase | 1-gen-2011 | Raffaelli, Nadia; Bocci, P.; Galeazzi, L.; Amici, Adolfo; Brunetti, L.; Ruggieri, Silverio; Reed, S.; Romine, M.; Osterman, A. L.; Rodionov, D.; Sorci, Leonardo | |
Structural biology of NAD metabolism in bacteria | 1-gen-2011 | Huang, N.; Eyobo, Y.; Sorci, Leonardo; Osterman, A. L.; Hong, Z. | |
NAD biosynthesis enzymes from the bacterial world as valuable tools for vitamin B3 mononucleotides quantitation in mammals | 1-gen-2012 | Carradori, R; Mori, V; Amici, Adolfo; Orsomando, Giuseppe; Sorci, Leonardo; Mazzola, F; Bocci, Paola; Ruggieri, Silverio; Raffaelli, Nadia | |
Glutamine versus Ammonia Utilization in the NAD Synthetase Family. | 1-gen-2012 | De Ingeniis, J; Kazanov, Md; Shatalin, K; Gelfand, Ms; Osterman, Al; Sorci, Leonardo | |
S. pyogenes is reliant on salvage of host pyridine precursors for NAD synthesis: implications for pathogenesis and antibacterial intervention | 1-gen-2012 | Sorci, Leonardo; Blaby, Ik; De Crécy Lagard, V; Osterman, A. | |
Quinolinate salvage and insights for targeting NAD biosynthesis in group A Streptococci. | 1-gen-2013 | Sorci, Leonardo; Blaby, Ik; Rodionova, Ia; De Ingeniis, J; Tkachenko, S; de Crécy Lagard, V; Osterman, Al | |
Genomics-Guided Analysis of NAD Recycling Yields Functional Elucidation of COG1058 as a New Family of Pyrophosphatases | 1-gen-2013 | Cialabrini, L.; Ruggieri, Silverio; Kazanov, M. D.; Sorci, Leonardo; Mazzola, Francesca; Orsomando, Giuseppe; Osterman, A. L.; Raffaelli, Nadia | |
NAD homeostasis in the bacterial response to DNA/RNA damage. | 1-gen-2014 | Sorci, Leonardo; Ruggieri, Silverio; Raffaelli, Nadia | |
Nicotinate phosphoribosyltransferase: a novel antiinfective target? | 1-gen-2014 | Sorci, Leonardo; Anton, Cheltsov; Massaccesi, Luca; Galeazzi, Roberta | |
Metabolic and Bactericidal Effects of Targeted Suppression of NadD and NadE Enzymes in Mycobacteria | 1-gen-2014 | Rodionova, Ia; Schuster, Bm; Guinn, Km; Sorci, Leonardo; Scott, Da; Li, X; Kheterpal, I; Shoen, C; Cynamon, M; Locher, C; Rubin, Ej; Osterman, A. L. | |
Characterization of bacterial NMN deamidase as a Ser/Lys hydrolase expands diversity of serine amidohydrolases. | 1-gen-2014 | Sorci, Leonardo; Brunetti, L; Cialabrini, L; Mazzola, Francesca; Kazanov, Md; D'Auria, S; Ruggieri, Silverio; Raffaelli, Nadia | |
Regulation of NAD biosynthetic enzymes modulates NAD-sensing processes to shape mammalian cell physiology under varying biological cues | 1-gen-2015 | Ruggieri, Silverio; Orsomando, Giuseppe; Sorci, Leonardo; Raffaelli, Nadia | |
Mycobacterial Nicotinate Mononucleotide Adenylyltransferase: STRUCTURE, MECHANISM, AND IMPLICATIONS FOR DRUG DISCOVERY | 1-gen-2015 | Rodionova, Irina A; Zuccola, Harmon J; Sorci, Leonardo; Aleshin, Alexander E; Kazanov, Marat D; Ma, Chen Ting; Sergienko, Eduard; Rubin, Eric J; Locher, Christopher P; Osterman, Andrei L. |
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