Tigecycline is an injectable antibacterial agent derived from the tetracyclines and classified by the manufacturer as a glycylcycline. Tigecycline was registered by the European Medicines Agency (EMEA) in May 2006 for parenteral use in complicated skin and skin-structure infections (CSSSIs) and complicated intra-abdominal infections (CIAIs) caused by Enterobacteriaceae (except Proteus spp., Morganella spp. and Providencia spp.), staphylococci, streptococci, Enterococcus faecalis and Enterococcus faecium. Tigecycline is active against microorganisms that have developed resistance to existing tetracyclines. This Technical Note is based on the EUCAST tigecycline rationale document (available on the EUCAST website: http://www.eucast.org). The rationale document includes more details and published references relating to the selection of EUCAST breakpoints.
EUCAST Technical Note on tigecycline / Kahlmeter, G.; Brown, D. F. J.; Canton, R.; Macgowan, A. P.; Mouton, J. W.; Rodloff, A.; Goldstein, F.; Odenholt, I.; Steinbakk, M.; Varaldo, Pietro; Hryniewicz, W.. - In: CLINICAL MICROBIOLOGY AND INFECTION. - ISSN 1198-743X. - 12:(2006), pp. 1147-1149. [10.1111/j.1469-0691.2006.01578.x]
EUCAST Technical Note on tigecycline
VARALDO, Pietro;
2006-01-01
Abstract
Tigecycline is an injectable antibacterial agent derived from the tetracyclines and classified by the manufacturer as a glycylcycline. Tigecycline was registered by the European Medicines Agency (EMEA) in May 2006 for parenteral use in complicated skin and skin-structure infections (CSSSIs) and complicated intra-abdominal infections (CIAIs) caused by Enterobacteriaceae (except Proteus spp., Morganella spp. and Providencia spp.), staphylococci, streptococci, Enterococcus faecalis and Enterococcus faecium. Tigecycline is active against microorganisms that have developed resistance to existing tetracyclines. This Technical Note is based on the EUCAST tigecycline rationale document (available on the EUCAST website: http://www.eucast.org). The rationale document includes more details and published references relating to the selection of EUCAST breakpoints.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
